Healing of Ischemic Leg Ulcers in Patients Treated With iSONIAzid — SONIA

Arterial Leg Ulcer Clinical Trial

Official title:
Healing of Ischemic Leg Ulcers: A Pilot Trial

Status Withdrawn

Clinical Trial Summary

The main objective of this trial is to study the healing effect of an oral drug (isoniazid) in patients with ischemic (arterial) leg ulcers defined by a systolic toe pressure <40 mm Hg.

Clinical Trial Description

Treatment of arterial ulcers is problematic. Previous pharmaceutical interventions with for example prostaglandins have produced only limited beneficial effects but have been associated with frequent adverse effects. Positive effects of isoniazid have been observed in a preclinical model of ischemic wound healing (Weinreich et al. Surgery 2010). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04802928
Study type	Interventional
Source	Pharma 2100
Contact
Status	Withdrawn
Phase	Phase 2
Start date	April 2008
Completion date	November 2008

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See also
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Recruiting	`NCT06255288` - Time to Heal (Wound, Healing, Dialogue, Nutrition)	N/A
Active, not recruiting	`NCT05007301` - Geko™ Cross Therapy Registry - Wound