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Arsenic Poisoning clinical trials

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NCT ID: NCT03893721 Not yet recruiting - Malnutrition, Child Clinical Trials

Effect of Chronic Arsenic Exposure on Malnutrition of Under Five Children

Start date: June 2019
Phase:
Study type: Observational

Early life malnutrition is associated with later life health problems, Particularly Stunting, which is a height-for-age Z score less than -2 standard deviation of World Health Organization median.Underweight is weight-for-age Z score less than -2 standard deviation of World Health Organization median. Wasting is weight -for- height Z score less than -2 standard deviation of World Health Organization median.

NCT ID: NCT03725592 Active, not recruiting - Arsenic Poisoning Clinical Trials

Strong Heart Water Study

SHWS
Start date: July 2, 2018
Phase: N/A
Study type: Interventional

Develop and evaluate the effectiveness of multi-level participatory interventions in reducing arsenic exposure among American Indian (AI) communities from North and South Dakota who participated in the Strong Heart Study (SHS).

NCT ID: NCT03127657 Completed - Clinical trials for Chronic Arsenic Poisoning

Effect of Cock's Comb Extract in the Treatment of Arsenical Skin Lesion

Start date: January 17, 2016
Phase: Phase 2
Study type: Interventional

Cock's comb extract is rich in hyaluronic acid, which is used as viscosupplementation injection and oral supplementation for osteoarthritis. Hyaluronic acid acts as humectants and topical moisturizing agent to the skin due to excellent moisturizing property. It has anti-inflammatory effect and used in the treatment of ulcer healing and to reduce the intensity of radioepithelitis. It is also used as a topical vehicle for the delivery of drug to the skin in actinic keratosis. In the case of arsenical keratotic nodule, topical application of hyaluronic acid may tends to decrease keratosis by repeated hydration of the skin. Therefore, the study will be conducted to determine any beneficial effect of topical application of cock's comb extract in the treatment of the patients with severe palmar arsenical keratosis.

NCT ID: NCT02908581 Completed - Clinical trials for Chronic Arsenic Poisoning

Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis

Start date: June 2016
Phase: Phase 2
Study type: Interventional

This study will be conducted to observe any change in fungal pattern on skin of arsenicosis patients before and after administration of iron (150 mg) and folic acid (0.5 mg) tablets.

NCT ID: NCT02468518 Completed - Clinical trials for Chronic Arsenic Poisoning

Effect of Vitamin E on Skin Aerobic Bacteria in Palmar Arsenical Keratosis

Start date: March 2015
Phase: Phase 2
Study type: Interventional

This study will be conducted to observe any change in aerobic bacterial pattern on the skin of arsenicosis patients before and after administration of vitamin E (200 IU) capsules.

NCT ID: NCT02429921 Completed - Arsenic Poisoning Clinical Trials

High-selenium Lentils Versus Arsenic Toxicity

Start date: October 2015
Phase: N/A
Study type: Interventional

About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases. This dietary trial intends to test the potential of high-selenium lentils, consumed as lentil soup, in reducing the arsenic body burden in an exposed Bangladeshi population, and in improving the overall health status. Arsenic-exposed families will be assigned to one of two groups. One group will eat lentils (50g/person/day) that are naturally high in selenium, the other group will receive lentils with low selenium content. This 6 months trial is randomized and double-blinded.

NCT ID: NCT02377635 Completed - Clinical trials for Arsenic Poisoning Chronic

Selenium and Arsenic Pharmacodynamics

SEASP
Start date: February 10, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical trial should prove that selenium can treat arsenic exposure in humans by promoting excretion. The new trial differs from previous trials in that participants will be maintained in a local clinic and provided with food and water from their home villages. The purpose of this study to determine the fate of selenium supplements in feces, urine and blood of volunteers living in conditions of high arsenic load in drinking water. The use of a clinic will enable monitoring of all intake and excretion of both arsenic and selenium, and will ensure that participants take their selenium doses or placebo as appropriate. This proof of concept is absolutely essential groundwork for any remediation strategy involving selenium supplements.

NCT ID: NCT02352987 Completed - Clinical trials for Chronic Arsenic Poisoning

Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the Treatment of Arsenical Palmar Keratosis

Start date: March 2015
Phase: Phase 2
Study type: Interventional

This study is designed to find out the effectiveness of combination of ethanol extract of neem leaf, propylene glycol (40%) and salicylic acid (10%) in the treatment of palmar arsenical keratosis.

NCT ID: NCT02235948 Active, not recruiting - Arsenic Poisoning Clinical Trials

Effects of Folic Acid Supplementation on Arsenic Lowering

Start date: July 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether folic acid supplementation are effective on arsenic lowering in a chronic, low-level arsenic exposed population.

NCT ID: NCT01748669 Completed - Clinical trials for Chronic Arsenic Poisoning

Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis

Start date: October 2011
Phase: Phase 2
Study type: Interventional

Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil capsule orally for 12 weeks to examine its effectiveness in reducing body arsenic load and clinical symptoms. Similar treatment with similar number of arsenic exposed controls and healthy volunteers will be included for comparison.