Arrhytmia in Psoriasis Clinical Trial
Official title:
Increased Risk of Atrial and Ventricular Arrhythmia in Long-lasting Psoriasis
Background:
Several reports have demonstrated an association between psoriasis and cardiovascular
diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers
used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess
homogeneity of cardiac repolarization and may be a risk for ventricular arrhythmias.
Aim: To search PWD and QTD in patients with psoriasis. Methods: Ninety-four outpatient
psoriasis patients and 51 healthy people were evaluated by physical examination, 12-lead ECG
and transthoracic echocardiography. Severity of the psoriasis was evaluated by psoriasis
Area and Severity Index (PASI).
Ninety-four outpatient psoriasis patients and 51 healthy people were included in the study. Patients having systemic hypertension, diabetes mellitus, history of ischemic heart disease, significant valvular heart disease, chronic obstructive pulmonary disease, hypo or hyper-thyroidism, renal failure or any associated systemic disease were excluded. Diagnosis of psoriasis was confirmed by dermatological examination and/or punch biopsy. Severity of the psoriasis was evaluated by psoriasis area and severity index (PASI). Patients were evaluated by physical examination, 12-lead electrocardiography and transthoracic echocardiography. ;
Observational Model: Case Control, Time Perspective: Prospective