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Clinical Trial Summary

This is a multi-site, retrospective chart review as well as a prospective study to evaluate histopathologic findings in liver samples from individuals with any UCD diagnosis. This study will be conducted at all Urea Cycle Disorders Consortium (UCDC) sites: Baylor College of Medicine in Houston, TX and Children's National Medical Center in Washington D.C.


Clinical Trial Description

Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism. With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this improved survival has led to unmasking of some long-term complications such as hepatic dysfunction and progressive fibrosis in a subset of patients. Hepatic complications in UCDs are quite variable and dependent upon the specific metabolic defect. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04908319
Study type Observational
Source Baylor College of Medicine
Contact Saima Ali, MSN
Phone 832-822-4183
Email saima.ali@bcm.edu
Status Recruiting
Phase
Start date February 24, 2022
Completion date June 30, 2025

See also
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