Clinical Trials Logo

Clinical Trial Summary

The overall objective is to evaluate the impact of sourdough fermented crisp bread on effects on appetite and postprandial glucose and insulin responses. Beneficial effects on appetite and postprandial insulin responses have been observed, particularly for unfermented rye crisp breads in a previous study. In the present study, the investigators evaluated how the intake of sourdough fermented rye crisp breads vs. unfermented rye crisp bread as well as a control refined wheat crisp bread product may affect self-rated appetite and postprandial insulin and glucose responses in healthy men and women in a meal-study. The investigators characterized intervention products with regards to microstructural and chemical features in order to elucidate underlying mechanisms for potential effects observed on appetite and postprandial metabolic responses.


Clinical Trial Description

Two commercial whole grain rye crisp breads processed differently (unfermented and sourdough fermented) and a refined wheat control product were tested in the study. The rye crisp bread products contained similar ingredients. All products provide similar amounts of available carbohydrates (about 30g). The total amount of test product is about 50-60g.

The specific primary aim of the study: To conduct a short-term breakfast intervention study in humans (n = 24) to compare the effect of 2 high-fiber rye crisp bread products processed in different ways (sourdough fermented or unfermented) and a refined wheat control crisp bread as part of a normal breakfast on self-rated appetite, postprandial glucose and insulin concentrations. Difference in post-prandial insulin response between products is the primary endpoint.

Secondary aim (conducted if significant effects in the primary endpoint have been demonstrated): To assess changes in hormones and their relation to self-perceived satiety, hunger and desire to eat and to differences in chemical and microstructural composition of the tested foods. ;


Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label


Related Conditions & MeSH terms


NCT number NCT02793297
Study type Interventional
Source Swedish University of Agricultural Sciences
Contact
Status Completed
Phase N/A
Start date January 2015
Completion date March 2016

See also
  Status Clinical Trial Phase
Completed NCT04219189 - The Acute Effect of Vaping on Food Intake N/A
Completed NCT02957318 - Effect of Potato Fiber on Appetite and Fecal Fat Excretion N/A
Completed NCT04378374 - The Effect of Pulse Flours on Blood Glucose, Satiety and Food Intake N/A
Completed NCT01199770 - Pasta Formulations, Portion Sizes and Their Effect on Appetite N/A
Recruiting NCT05443347 - Activity, Adiposity, and Appetite in Adolescents 2 Intervention N/A
Withdrawn NCT02111486 - Effect of Certain Breakfasts on Appetite Control N/A
Completed NCT02379312 - Comparison of the Satiety Effect of a Very Low Energy Foam With Normal Energy Foams N/A
Completed NCT01222845 - Glycaemic, Insulinaemic and Appetite Responses to Two Different Types of Porridge N/A
Completed NCT03701503 - The Comparison of PYY, Ghrelin, GLP1, Glucose Level, Level of Satiety, and Ad Libitum Intake in Obese and Non-Obese Patients After Breakfast With Balanced Macronutrient Composition N/A
Completed NCT03697486 - The Effect of Breakfast With Different Macronutrient Composition on PYY, Ghrelin, GLP-1,Glucose Level, VAS for Hunger, VAS for Satiety and Ad Libitum Intake 4 Hours After Breakfast in Obese Women N/A
Completed NCT03900130 - The Omnibus Satiety Metric: Predicting Satiety in Humans Through Brain, Blood, and Subjective Data N/A
Completed NCT05012046 - Effect of 100% Orange Juice on Food Intake and Glycemic Response in Adults N/A
Completed NCT02484625 - The Effect of Dairy and Non-Dairy Snacks on Food Intake, Subjective Appetite in Children N/A
Withdrawn NCT01246492 - The Effect of Artificial Sweeteners on Blood Glucose Response N/A
Completed NCT05534152 - Effect of Sumac on Appetite and Food Intake N/A
Completed NCT03974165 - Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation N/A
Completed NCT01592149 - Survey of Prevalence of Loss of Appetite in Subject With Health Disorders N/A
Recruiting NCT01121783 - The Effect of Lactisole on the Responses to Glucose Solution N/A
Completed NCT01102907 - Effect of Food Form on Satiety and Gastric Emptying
Completed NCT03128684 - The Effects of Lentil-containing Food Products on Satiety and Food Intake N/A