Apnoeic Oxygenation Clinical Trial
Official title:
Apnoeic Oxygenation by Nasal Cannula During Airway Management in Children Undergoing General Anaesthesia: A Pilot Randomised Controlled Trial"
Airway management is a core clinical skill in anaesthesia. Pre-oxygenation prior to induction
of anaesthesia is standard practice to prevent desaturation. Apnoeic oxygenation in adults is
effective and prolongs the time to desaturation. The effectiveness of apnoeic oxygenation in
the adult is well document, however evidence in the paediatric is lacking. Therefore, the aim
of this study was to investigate the effectiveness of apnoeic oxygenation during airway
management in children.
This was a pilot randomised controlled trial. Patients were randomised to either receive
apnoeic oxygenation or standard care during the induction of anaesthesia. The primary outcome
was the duration of safe apnoea, defined as a composite of the time to first event, either
time for SpO2 to drop to 92% or time to successfully secure the airway, and the lowest SpO2
observed during airway management. Secondary outcomes were number of patients whose SpO2
dropped below 95% and number of patients whose SpO2 dropped below 92%.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03478774 -
Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates
|
N/A | |
| Completed |
NCT03738722 -
Positive Airway Pressure Under Apnoeic Oxygenation With Different Flow Rates in Nasal Cannula Therapy
|
N/A |