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Apnea clinical trials

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NCT ID: NCT00916773 Recruiting - Clinical trials for Sleep Apnea, Obstructive

Pulmonary Disorders During Exercise in Patients With Obstructive Sleep Apnea

Start date: April 2009
Phase: N/A
Study type: Interventional

Purposes: 1. To investigate whether patients with severe obstructive sleep apnea syndrome (OSAS) are at higher risk for exercised-induced bronchoconstriction (EIB) due to baseline airway inflammation compared with age, gender, and body mass index (BMI)-matched controls. 2. To investigate the effect of 3-month continuous positive airway pressure (CPAP) therapy on EIB for patients with severe OSAS.

NCT ID: NCT00915499 Completed - Clinical trials for Complex Sleep Apnea Syndrome

Complex Sleep Apnea Syndrome (CompSAS) Resolution Study

CompSAS
Start date: May 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether adaptive servo-ventilation (ASV) or continuous positive airway pressure (CPAP) is better at treating complex sleep apnea over time.

NCT ID: NCT00912457 Recruiting - Clinical trials for Obstructive Sleep Apnea

Donepezil Treatment for Sleep Apnea Patients

doneapnea
Start date: March 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effects of the anticholinesterase drug donepezil on sleep apnea patients. Sleep structure and respiratory parameters will be analyzed by polysomnography.

NCT ID: NCT00912171 Completed - Clinical trials for Obstructive Sleep Apnea Syndrome

Efficacy of Oral Leukotriene in Long Term Therapy of Mild and Moderate Obstructive Sleep Apnea Syndrome in Children

SB-OSAS
Start date: January 2009
Phase: Phase 4
Study type: Interventional

The aim of the project is to evaluate whether therapy with leukotriene may be a valid therapeutic approach in children with adenotonsillar hypertrophy and with mild and moderate obstructive sleep apnea syndrome (OSAS) and to evaluate whether leukotriene is less, equally or more efficient than nasal steroid.

NCT ID: NCT00901771 Completed - Clinical trials for Sleep Apnea, Obstructive

Study of Provent Treatment of Obstructive Sleep Apnea in Patients Who Are Non-compliant With CPAP

Start date: May 2009
Phase: N/A
Study type: Interventional

The primary objective of the proposed investigation is to evaluate the efficacy of the Provent device in a sample of OSA patients who have either refused or been non-adherent with PAP treatment. Both initial efficacy (evaluated after approximately one week with Provent) and efficacy after approximately 5 weeks in patients who demonstrate initial efficacy will be assessed. A secondary objective is to assess adherence with Provent treatment during the 5-week evaluation period.

NCT ID: NCT00885573 Completed - Clinical trials for Sleep Apnea Syndrome

Pharyngeal Sensitivity in Diagnosis Algorithm for Sleep Apnea Syndrome

SENSITEST
Start date: December 2008
Phase: N/A
Study type: Interventional

Pharyngeal sensitivity is a determinant parameter of pharyngeal functioning, particularly regarding protective dilator reflexes of upper airway. Preliminary results have suggested that the use of this parameter in diagnosis algorithm such as linear discriminant analysis and random forest could predict the presence of sleep apnea syndrome in almost 98% of patients. Our study aims at validating a new diagnosis method of sleep disordered breathing which will be compared with nocturnal polysomnography, the reference method to diagnose sleep disordered breathing. Pharyngeal sensitivity will be measured using the SENSITEST device which allows an automatic measurement of the pharyngeal sensation. The use of this parameter in diagnosis algorithm will be compared with polysomnographic results.

NCT ID: NCT00883376 Completed - Clinical trials for Obstructive Sleep Apnea Syndrome

Classification of Stanford for Snore as Factor of Aggravation of the Apnea Hypopnea Index (AIH) in Patients With Obstructive Sleep Apnea Syndrome (OSAS)

StanforAIH
Start date: January 2007
Phase: N/A
Study type: Observational

Introduction: Obstructive sleep apnea syndrome (OSAS) became an important and prevalent illness in recent years. The population occidental becomes fat each time, and this symptom is associated the biggest risk for the OSAS. Snore presence is extremely associated with OSAS. Snoring is present in about 90 - 95% of the patients with OSAS. Objectives: Evaluate the influence in the Stanford classification as predictor factor of gravity of the OSAS. Materials and Methods: They evaluated and classified 107 patients, Classification of Mallampati, Friedman, Classification of Stanford and how much the gravity of the OSAS for the AIH.

NCT ID: NCT00883025 Completed - Clinical trials for Obstructive Sleep Apnea Syndrome

Correlation Between Friedman Classification and the Apnea Hypopnea Index (AIH) in a Population With Obstructive Sleep Apnea Syndrome (OSAS)

FriedmAIH
Start date: February 2007
Phase: N/A
Study type: Observational

Introduction: OSAS is an important disease in the actual medic scene. It is important for correlation with chronic cardiovascular disease that leaves an increase in morbimortality and socioeconomic disability to patients with apnea. Objectives: Determinate the correlation between Friedman Classification and the obstructive sleep apnea syndrome (OSAS) gravity through AHI (Apnea Hypopnea Index) in patients with OSAS for surgical indication and evaluation. Materials and Methods: The investigators evaluated and classified 84 patients, in the scale of Epworth, Friedman and how much the gravity of the SAHOS for the AHI.

NCT ID: NCT00881985 Completed - Clinical trials for Obstructive Sleep Apnea

Effect of Continuous Positive Airway Pressure for Treatment of Obstructive Sleep Apnea on Resistant Hypertension

Start date: March 2009
Phase: N/A
Study type: Interventional

The objectives of this study are to investigate the effect of continuous positive airway pressure (CPAP) treatment on blood pressure control and vascular inflammation in subjects with resistant hypertension and moderate obstructive sleep apnea (OSA).

NCT ID: NCT00880165 Completed - Clinical trials for Obstructive Sleep Apnea

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

VSATT
Start date: November 2006
Phase: N/A
Study type: Interventional

This research study is comparing home and in-laboratory testing of veterans with suspected obstructive sleep apnea, a common breathing disorder during sleep. It is hoped that home testing will be equally effective in improving quality of life but have lower cost than in-lab testing. These findings will allow veterans to have greater access to diagnosis and treatment of their sleep apnea.