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Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins

Aortic Stenosis Clinical Trial

Official title:
Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins

Clinical Trial Summary

Aortic stenosis (AE) is a disease that has been increasing steadily in recent years in most countries, including Spain.Risk factors for the development of AE include age, hypercholesterolemia, diabetes mellitus and arterial hypertension, the classic risk factors for the development of atherosclerosis. However, lipid-lowering therapy with statins and ezetimibe has not been shown to reduce the risk of long-term progression of AE by unknown mechanisms. All this suggests that subjects with HFhe have a high risk of developing AD, which has not been shown by the high coronary mortality in this population that precedes aortic calcification

Clinical Trial Description

The study includes a single clinical visit with collection of clinical data, blood extraction and the performance of a transthoracic echocardiogram. This visit may be made on different days, but always within 30 days of signing the informed consent. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03310671
Study type Observational [Patient Registry]
Source Instituto Aragones de Ciencias de la Salud
Contact Fernando Civeira
Phone 976765500
Email civeira@unizar.es
Status Recruiting
Phase N/A
Start date July 18, 2017
Completion date July 18, 2018
View Details
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