Frailty Assessment Before Cardiac Surgery & Transcatheter Interventions

Status Completed

Clinical Trial Summary

Frailty is a state of decreased physiologic reserves and vulnerability to stressors. Several tools exist to measure frailty, some based on physical tests and others on questionnaires, yet there is no agreement on which tool to recommend. This multi-center prospective cohort study is aimed at comparing various frailty assessment tools to determine which best predicts death or major complications after cardiac surgery or transcatheter intervention. The population of interest is elderly patients with severe aortic stenosis undergoing surgical or transcatheter aortic valve replacement. The frailty assessment tools under investigation include composite frailty scales, physical performance tests, muscle mass, and biomarker expression. The overall objective is to improve our ability to predict risk by measuring frailty using the optimal tool in elderly cardiovascular patients.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Aortic Stenosis
Aortic Valve Stenosis
Cardiac Valve Replacement Complication
Constriction, Pathologic
Fragility

Clinical Trial Details

NCT number	NCT01845207
Study type	Observational [Patient Registry]
Source	Jewish General Hospital
Contact
Status	Completed
Phase	N/A
Start date	January 2012
Completion date	March 2016

View Details

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