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Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

Aortic Stenosis Clinical Trial

Official title:
Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

Clinical Trial Summary

The goal of this observational study is to assess the changes of ascending aortic diameter in patients undergoing transcatheter aortic valve replacement. The main questions it aims to answer are: 1. whether the ascending aortic diameter increases or remains stable after transcatheter aortic valve replacement, especially in patients with preoperative ascending aortic dilatation; 2. the determinants of postoperative ascending aortic dilatation.

Clinical Trial Description

Ascending aortic (AA) dilatation occurs frequently in patients with aortic stenosis (AS). For patients who are candidates for transcatheter aortic valve replacement (TAVR), simultaneous repair of a dilatated AA is technically difficult. As the indications for TAVR have extended to low-risk patients and patients with bicuspid aortic valve , AA dilatation should be considered as a new criterion to refine risk stratification in patients undergoing TAVR. In this observational study, we aim to evaluate the changes of AA diameters and identify the determinants post-TAVR AA dilatation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05739253
Study type Observational
Source China National Center for Cardiovascular Diseases
Contact Xiangbin Pan, Dr
Phone 0086-010-88396666
Email panxiangbin@fuwaihospital.org
Status Recruiting
Phase
Start date March 22, 2022
Completion date March 21, 2025
View Details
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