Prospective Feasibility Study of Point-of-care Ultrasound in Suspected

Status Not yet recruiting

Clinical Trial Summary

Aortic dissection is an uncommon and serious pathology. Its diagnosis is difficult because of the varied and silent clinical presentations. The development of ultrasound in emergency medicine is an asset in certain pathologies. The aim of this study is therefore to study the feasibility of a protocol integrating clinical ultrasound in the suspicion of acute aortic dissection in the hospital setting. This study is a single-center prospective interventional study. In which the investigators perform ultrasound in patients with suspected acute aortic dissection in the emergency department. If the protocol is feasible and if it allows a saving of time in the diagnosis or an increase in diagnoses, the investigators will be able to evoke a profitability to the systematic realization of this examination.

Clinical Trial Description

H0: patient selection and inclusion: - Presentation of the study - Delivery of the information note / no objection to the patient if he/she is in a state to consent - Emergency procedure: In accordance with article L-1122-1-3 of the public health code, patients may be included in the study at the initiative of the physician without seeking prior consent. This procedure will be associated with a prior call to the relatives to obtain an oral consent in principle (traced in the patient's medical file), while waiting for the delivery of the information note / no objection to the relatives and then to the patient as soon as his condition allows it. H1: inclusion interview then : Medical interrogation (retrospective collection if already done / but additional requests if missing data). Clinical examination (complementary if missing data). Ultrasound with 3 ultrasound sections to be performed: parasternal long axis, supra-sternal and abdominal, looking for the following signs: Direct signs: presence of an intimal flap, intramural aortic hematoma > 5mm, penetrating aortic ulcer. Indirect signs: pericardial effusion, aortic dilatation ≥ 4 cm, tamponade (1). H4: retrospective collection of the results of complementary examinations if any, biological and radiological, and collection of the final diagnosis retained. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05897476
Study type	Interventional
Source	Centre Hospitalier Universitaire de Besancon
Contact	Christian DAGUERRE, MD
Phone	+33381668853
Email	daguerrechristian@laposte.net
Status	Not yet recruiting
Phase	N/A
Start date	July 2023
Completion date	June 2024

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05582967` - The DAShED (Diagnosis of Aortic Syndrome in the ED) Study
Terminated	`NCT04116684` - Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients	N/A
Completed	`NCT02086136` - Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection
Recruiting	`NCT02201589` - Feasibility of Endovascular Repair Of Ascending Aortic Pathologies	N/A
Recruiting	`NCT03948555` - Magnetic Resonance Imaging (MRI) for Aortic Dissection to Visualise Inflammation
Enrolling by invitation	`NCT05912608` - Optimal Strategy for Repair of Type A Acute Aortic Dissection
Recruiting	`NCT03707743` - Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE)
Enrolling by invitation	`NCT00583817` - Endovascular Treatment of Thoracic Aortic Disease	N/A
Recruiting	`NCT05073991` - Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.
Not yet recruiting	`NCT02523300` - Glucocorticoid on the Prognosis of TEVAR	N/A
Completed	`NCT01197651` - Aortic-Stent-Register	N/A
Recruiting	`NCT04471909` - NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness	N/A
Not yet recruiting	`NCT06044259` - Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection	N/A
Completed	`NCT05039814` - Prediction of Postoperative Acute Kidney Injury in Patients With Acute Type A Aortic Dissection Using Cystatin C
Recruiting	`NCT03780738` - A Validation Study of The Relationship Between ALDH2 and Aortic Dissection
Completed	`NCT03647566` - 18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
Enrolling by invitation	`NCT05800743` - Evaluation of the GORE® Ascending Stent Graft	N/A
Recruiting	`NCT03347812` - Clinical Study for Evaluating the Safety and Efficacy of Total Endovascular Aortic Arch Repair	N/A
Completed	`NCT05044494` - Surgery for Delay-recognized or Defer-operated Type A Aortic Dissection
Terminated	`NCT02958098` - My Research Legacy Pilot Study

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Prospective Feasibility Study of Point-of-care Ultrasound in Suspected Aortic Dissection — FESDAU

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms