Effects of Maternal Interpretation Biases on Child Anxiety and Related Responses

Anxiety Disorders Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02095340
• Other study ID #: 2014-0035
• Status: Completed
• Phase: N/A
• Start date: May 2014
• Est. completion date: April 30, 2018

Study information

• Verified date: February 2020
• Source: University of Houston
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to expand our understanding of the intergenerational transmission of cognitive risk for childhood anxiety disorders by examining whether changes in maternal interpretations of situations result in changes in child interpretations and child anxiety.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 210
• Est. completion date: April 30, 2018
• Est. primary completion date: April 30, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 8 Years to 12 Years

Eligibility

Inclusion Criteria:

• Children ages 8-12

• Children with primary diagnosis of anxiety disorder

• Mothers with clinical levels of anxiety symptoms on the Depression, Anxiety, and Stress Scales (DASS; Lovibond & Lovibond, 1995)

Exclusion Criteria:

• Physical disability impairing ability to use a computer

• Intelligence Quotient <80

• Reading comprehension and fluency composite <75

• Concurrent primary diagnosis of any non-anxiety disorder

• Currently receiving psychological or pharmacological treatment for anxiety

• Danger to self/others

• Non-English speaking child/parent

• Maternal current involvement in cognitive-behavioral therapy

• Maternal changes in pharmacological treatment in the 12 weeks prior to enrollment.

Related Conditions & MeSH terms

• Anxiety Disorders

Intervention

Other:
• Positive Interpretation Bias Training

• Neutral Interpretation Bias Training

Locations

Country	Name	City	State
United States	University of Houston	Houston	Texas

Sponsors (1)

Lead Sponsor	Collaborator
University of Houston

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Word Sentence Association Paradigm	Proportion of threatening (versus nonthreatening) interpretations made on the Word Sentence Association Paradigm (WSAP). Scores range from 0 to 1. Higher scores mean a worse outcome, that is, more negative interpretations.	Participants will be assessed, on average, within 20 minutes after the intervention.
Primary	Maternal Anxious Behavior Coded by Independent Observers.	Maternal anxious behavior coded by independent observers on a 0 - 4 scale. Higher numbers indicated more observed anxious behaviors.	Immediately after the intervention, an average of 10 minutes.