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Clinical Trial Summary

Background : Epidural anaesthesia is associated in abdominal surgery with reduced pain and postoperative respiratory complications together with quicker recovery of bowel function. Currently, no studies have been able to prove its ability to reduce length of stay in intensive care and high-dependency units.

Purpose : The aim of this study is to demonstrate that epidural anaesthesia reduces length of stay in intensive care unit after abdominal surgery under laparotomy.


Clinical Trial Description

There are currently two methods of analgesia in postoperative abdominal surgery : patient-controlled analgesia (PCA) with opioids and epidural analgesia.

No international recommendations regarding the use of either of these techniques have yet been written. Epidural analgesia is superior to intravenous morphine, including during mobilization and coughing. It also reduces respiratory complications and optimizes postoperative rehabilitation. Nevertheless, mortality is not improved with this technique. Few publications exist on the optimization of the duration of hospitalization in the intensive care unit. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms

  • Abdomino-perineal Amputation Under Laparotomy
  • Anterior Resection of Rectum Under Laparotomy
  • Colectomy Left/Right/Total Under Laparotomy
  • Extended Ileal Resection Under Laparotomy
  • Rectosigmoidal Resection Under Laparotomy
  • Total Proctocolectomy Under Laparotomy

NCT number NCT01470846
Study type Interventional
Source University Hospital, Limoges
Contact
Status Terminated
Phase Phase 4
Start date November 2011
Completion date April 2013