Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release

Anterior Knee Pain Syndrome Clinical Trial

Official title:

Use of Hyaluronic Acid Injection After Arthroscopic Lateral Release in Patellar Compression Syndrome With Degenerative Cartilage Changes: Randomized Control Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04134611
• Other study ID #: HMU/Sherwan6
• Status: Completed
• Phase: N/A
• Start date: June 1, 2017
• Est. completion date: March 20, 2020

Study information

• Verified date: June 2020
• Source: Hawler Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

Description:

This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: March 20, 2020
• Est. primary completion date: March 10, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 26 Years to 47 Years

Eligibility

Inclusion Criteria:

• Lateral patellar compression syndrome

Exclusion Criteria:

• Patellar instability.

• Smoking.

• Diabetes Mellitus.

• Previous knee surgery.

Related Conditions & MeSH terms

• Anterior Knee Pain Syndrome
• Patellofemoral Pain Syndrome
• Syndrome

Intervention

Device:
• Hyaluronic acid injection
Injection of Hyaluronic acid in knees of those who has degenerative changes after arthroscopic treatment of lateral patellar compression syndrome
• No injection of Hyaluronic acid
No injection of Hyaluronic acid was done

Locations

Country	Name	City	State
Iraq	Sherwan Hamawandi	Erbil

Sponsors (1)

Lead Sponsor	Collaborator
Hawler Medical University

Country where clinical trial is conducted

Iraq, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Visual analogue score of knee pain	Visual analogue score of knee pain describe knee pain from degree 0 where no pain to degree 10 where is severe pain	The VAS for knee pain was measured 24 months after operation
Primary	Kujala score	Kujala score questionnaire up to 100	Preoperative assessment and 2 year postoperatively