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Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial

Anesthesia Clinical Trial

Official title:
Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial

Clinical Trial Summary

This study will compare an opioid free anesthetic, using dexmedetomidine, to a traditional opioid based anesthetic, using fentanyl, for patients undergoing cardiac surgery with regards to hemodynamic stability in the first 10 minutes after induction.

Clinical Trial Description

This is a single center, blinded, prospective, randomized controlled trial. A total of 158 subjects (79 subjects in each arm) are planned. The control group will receive a traditional cardiac anesthetic using opioids, for which induction will include fentanyl and propofol. The experimental arm will receive an opioid free anesthetic with an induction bolus of dexmedetomidine and propofol. The investigators hypothesize that using the opioid free technique will be more hemodynamically stable within the first 10 minutes of induction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04197570
Study type Interventional
Source Benaroya Research Institute
Contact
Status Completed
Phase Phase 3
Start date February 4, 2020
Completion date March 14, 2020
View Details
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