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General Anesthesia Exposure and Neurodevelopmental Outcome in Pediatrics — GAP  

Anesthesia Clinical Trial

Official title:
General Anesthesia Exposure and Neurodevelopmental Outcome in Pediatrics

Clinical Trial Summary

This study investigates the impact of different levels of anesthesia exposure on children's neurocognitive development and evaluates the concurrent validity of different methods that assess neurodevelopmental outcome.

Clinical Trial Description

The US Food and Drug Administration (FDA) recently released an official warning regarding the potentially harmful impact of repeated and prolonged (more than three hours) general anesthesia on the child's brain. The potential impact of anesthesia highlights the importance of remediating the need for repeated and prolonged surgery with accompanying anesthesia exposure in a time of cerebral vulnerability and if possible, delay exposure to avoid potentially preventable harm. Therefore, it is crucial to better understand the impact of (different durations and frequencies of) anesthesia exposure on neurodevelopment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04604106
Study type Observational
Source Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Contact Sanne Maat, MD
Phone 0031650100868
Email s.c.maat@amsterdamumc.nl
Status Recruiting
Phase
Start date October 21, 2020
Completion date March 2023
View Details
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