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Anesthesia clinical trials

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NCT ID: NCT05050656 Completed - Anesthesia Clinical Trials

Oral Duloxetine as a Premedication for Postoperative Pain Control

Start date: March 15, 2021
Phase: Phase 4
Study type: Interventional

The purpose of the study is to use duloxetine as premedication in Anterior cruciate ligament repair under spinal anesthesia and evaluate the effect on onset and duration of spinal anesthesia and postoperative pain control.

NCT ID: NCT05046925 Not yet recruiting - Anesthesia Clinical Trials

PACU for Postoperative Care After Major Thoracic and Abdominal Surgery

Start date: October 1, 2021
Phase:
Study type: Observational

The aim of this study is to demonstrate the efficacy and safety of a specialised post-anaesthetic care unit (PACU) to a conventional intensive care unit (ICU) in adult patients after major thoracic and abdominal surgery. A better understanding of PACU for postoperative care is likely to reduce mortality and postoperative complications.

NCT ID: NCT05045352 Completed - Anesthesia Clinical Trials

Echogenic Versus Non-echogenic Needles for Venous Access

Start date: January 12, 2022
Phase: N/A
Study type: Interventional

Randomized controlled intervention study comparing echogenic needles with non echogenic needles for ultrasound guided venous access in the subclavian vein.

NCT ID: NCT05028049 Not yet recruiting - Anesthesia Clinical Trials

Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau Area

Start date: August 30, 2021
Phase:
Study type: Observational [Patient Registry]

Purpose: 1. To compare the incidence of postoperative hyperalgesia induced by remifentanil in patients undergoing gynecological laparoscopic surgery in plateau and plain areas 2. To compare the peri-operative analgesic requirements of patients in plain and plateau areas

NCT ID: NCT05026788 Active, not recruiting - Covid19 Clinical Trials

Impact of COVID-19 Pandemic on Orthopaedic Practice

COVERT
Start date: March 17, 2020
Phase:
Study type: Observational

The COVERT Collaborative is led by a group of academic surgeons that is looking into the impact of the unprecedented COVID-19 pandemic on Trauma and Orthopaedic practice. This will involve both trauma and elective procedures, as well as mortality rates, operative and anaesthetic case mix. The information will help to shape service reconfiguration and enhance patient-specific treatment especially in the threat of potential subsequent waves and future pandemics.

NCT ID: NCT05024084 Recruiting - Anesthesia Clinical Trials

Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth

Start date: September 5, 2021
Phase: Phase 4
Study type: Interventional

Minimal flow anesthesia has economic and environmental advantages in addition to providing earlier recovery following general anesthesia. There is a paucity of data concerning the effect of minimal flow anesthesia (fresh gas flow <0,5 l/min) on recovery parameters. The primary objective of this study is to compare the recovery parameters of desflurane and sevoflurane in minimal flow anesthesia while the secondary objective is to compare the effect of these agents on anesthetic depth using bispectral index.

NCT ID: NCT05023356 Not yet recruiting - Anesthesia Clinical Trials

Non-contact Vital Signs Monitoring in Anesthesia

Start date: September 10, 2021
Phase:
Study type: Observational

The purpose of this study is to monitor vital signs with contact and non-contact monitors in patients during anesthesia, and analyze the signal differences between the two monitors.

NCT ID: NCT05021263 Completed - Anesthesia Clinical Trials

Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?

Start date: May 27, 2022
Phase: Phase 3
Study type: Interventional

This study is a randomized, double blind controlled trial examining the impact of incorporating a single intraoperative intravenous magnesium bolus and infusion into a preexisting Enhanced Recovery After Surgery (ERAS) protocol for colorectal surgery in place of preoperative oral pregabalin. These protocols are pathways designed with the goal of achieving early surgical recovery by utilizing a constellation of perioperative care techniques that include the use of opioid-sparing pain medications, minimally invasive approaches, and prevention of post-operative nausea and vomiting, among others. Intravenous magnesium has shown to be an effective non-opioid analgesic in abdominal surgeries that decreases total opioid consumption, pain, and improves recovery. The purpose of this study is to evaluate whether or not the addition of intravenous magnesium to our institutional ERAS protocol will improve specific outcome measures, and provide additional benefits when compared to oral preoperative pregabalin. The primary outcome is the patient's quality of recovery based on the "Quality of Recovery - 40 Questionnaire" (QOR 40), and secondary outcomes will be opioid consumption, pain, shivering, sedation scores, acute kidney injury, gastrointestinal function, respiratory function, and hospital length of stay.

NCT ID: NCT05005494 Not yet recruiting - Anesthesia Clinical Trials

Hypnotic and Anti-nociceptive Components of Magnesium

Start date: September 1, 2021
Phase: Phase 4
Study type: Interventional

The aim of our study is to evaluate the effect of magnesium on the hypnotic effect of propofol.

NCT ID: NCT04998435 Completed - Anesthesia Clinical Trials

Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy

Start date: August 11, 2021
Phase: N/A
Study type: Interventional

Nowadays, Percutaneous Nephrolithotomy (PCNL) has been the surgical procedure of choice for renal stones larger than 2cm or staghorn stones. Yet, the associated postoperative pain is a major drawback. The regional anesthetic management of pain in PCNL operation has been of great concern. The introduction of ultrasound guided erector spinae plane block and paravertebral plane block has been under great focus regarding the efficacy of postoperative pain management. Paravertebral plane block (PVB) is a regional nerve block technique that depends on local anesthetic injection adjacent to the vertebra to block spinal nerve roots in a dermatomal distribution. Erector spinae plane block (ESPB) is a newer regional anesthesia technique that depends on injecting local anesthetic (LA) in a plane between the transverse process and erector spinae muscle. The LA diffuses into the paravertebral space and spreads on both rami (dorsal and ventral) of spinal nerves through spaces between adjoining vertebrae. The aim of this study is to compare the effect of ultrasound guided Paravertebral blockade versus Erector spinae blockade on postoperative opioid use as well as postoperative pain control in patients undergoing unilateral PCNL.