Phentolamine Mesylate as a Reversal of Local Anesthesics

Status Completed

Clinical Trial Summary

Oraverse © (Phentolamine mesylate) is a product designed to reverse the effect of local anesthetics used in dentistry. Its main objective is to reduce the postoperative period during which the patient suffers from the lack of sensitivity in the perioral soft tissues, it is an obvious discomfort, a difficulty to speak or eat, and sometimes a risk of self-injury in the lips and / or tongue .

The product was approved by the FDA in 2008 although the introduction in Spain has not occurred until December 2015. There are numerous studies that support its use, its effectiveness and safety, although none of the Spanish population, who have not yet had the opportunity to experience it.

Clinical Trial Description

PURPOSE OF THE STUDY:

To analyze the response of Oraverse in patients receiving complete oral disinfection treatment, after administration of Lidocaine 2% 1/80000, Articaine 4% 1/200000 or Bupivacaine 0,5% 1:200000 in mandible, in comparison with the contralateral control side. ;

Study Design

Related Conditions & MeSH terms

Anesthesia, Local

Clinical Trial Details

NCT number	NCT03740386
Study type	Interventional
Source	León Formación
Contact
Status	Completed
Phase	N/A
Start date	January 1, 2016
Completion date	November 9, 2018

View Details

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