Anesthesia, General Clinical Trial
Official title:
The Effect of Frontal Electromyogram (F-EMG) Activity on the Entropy Index Behavior During General Anesthesia
This study evaluates the effect of frontal EMG activity on Entropy index in burst suppression level of propofol anesthesia and surgery
This is an academic observational study, where EEG is recorded during conventional
propofol-remifentanil-rocuronium anesthesia and surgery in informed, consenting adults,
during their surgical operations in Tampere University Hospital. The patients will be
informed about the possibility to participate during their preoperative visit, and the
approval will be asked on arrival in the day of surgery, before premedication.
The course of anesthesia will not be changed. The monitoring of the anesthetic state will be
conventional: Heart rate, blood pressure, oxygen saturation of blood, Entropy Index,
neuromuscular blockade will be monitored, as is the case in all surgical patients under
general anesthesia in Tampere University Hospital. Any further monitoring will apply
depending on the specific needs of the particular patient. Entropy Index data, EEG data and
neuromuscular blockade data will be recorded on computer and analyzed later at GE Healthcare
R&D Department, Helsinki, Finland, by Dr. Mika Särkelä. All data leaving Tampere University
Hospital will be anonymized.
Anesthetic induction will be given in a conventional way (intravenous propofol and
remifentanil, followed by intravenous rocuronium). EEG waveform is monitored with Entropy
module. Neuromuscular blockade will be monitored with EMG-NMT module (GE-Healthcare). The
data collection (Entropy, EEG, neuromuscular transmission (NMT) data) will last at least
until skin incision.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06063798 -
Respiratory Effects of Flow-Controlled Ventilation and Jet Ventilation in Patients Undergoing Laryngotracheal Surgery
|
N/A | |
| Not yet recruiting |
NCT05035069 -
Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR
|
Phase 4 | |
| Completed |
NCT03861364 -
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
|
Phase 4 | |
| Completed |
NCT02711280 -
The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in Children
|
N/A | |
| Completed |
NCT01199471 -
Estimate the Behavior of Chinese Anesthesiologists Practicing General Anesthesia With Sevoflurane
|
N/A | |
| Completed |
NCT00917033 -
Tracheal Intubation of Morbidly Obese Patients. GlideScope Versus Direct Laryngoscopy
|
Phase 4 | |
| Completed |
NCT00391885 -
Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy
|
Phase 4 | |
| Completed |
NCT00552617 -
A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971)
|
Phase 2 | |
| Completed |
NCT03705026 -
Relationship Between Genetic Polymorphism and Postoperative Nausea and Vomiting in Chinese Han Population
|
||
| Completed |
NCT00552929 -
A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)
|
Phase 2 | |
| Completed |
NCT00475215 -
Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)
|
Phase 3 | |
| Completed |
NCT00298831 -
Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)
|
Phase 3 | |
| Recruiting |
NCT03943745 -
EEG Changes During Induction of Propofol Anesthesia
|
||
| Completed |
NCT03697642 -
Nasopharyngeal Airway Guide Nasogastric Tube Placement
|
N/A | |
| Completed |
NCT04595591 -
Observation of Propofol Titration at Different Speeds
|
N/A | |
| Not yet recruiting |
NCT05841316 -
The ED95 Dose of Sugammadex to Reverse Rocuronium-Induced Deep Neuromuscular Block Back to Shallow Neuromuscular Block
|
||
| Completed |
NCT04532502 -
Impact of Anesthetic Environment the Sex Ratio of the Children of Female Assistants
|
||
| Completed |
NCT03330236 -
EEG - Guided Anesthetic Care and Postoperative Delirium
|
N/A | |
| Recruiting |
NCT06205212 -
High-flow Nasal Oxygenation During Preoxygenation and Atelectasis
|
N/A | |
| Completed |
NCT00379613 -
Use of Sugammadex Administered at 5 Minutes After Administration of 1.2 mg/kg Esmeron® (19.4.205)(P05942)
|
Phase 2 |