Anemia Clinical Trial
Official title:
An Intravenous Iron Based Protocol for Optimizing Haemoglobin in Anaemic Patients Prior to Fast-track Hip and Knee Arthroplasty - An Observational Follow up Study
This observational study follows a cohort of patients scheduled for elective hip- or knee surgery but has preoperative anemia and are treated with Intravenous (IV) iron prior to surgery according to a recently introduced standardized treatment protocol at 6 high-volume surgical centres.
Patients presenting with preoperative anaemia prior to hip and knee arthroplasty has a high
risk of receiving allogeneic blood transfusion and anaemia has been associated with
increased postoperative morbidity and mortality. While IV-iron administration may raise Hb
prior to surgery, existing guidelines for addressing and treating preoperative anaemia is
not widely implemented for patients scheduled for elective total joint arthroplasty (TJA) in
Denmark. In addition, causes of preoperative anaemia and the efficacy of preoperative
IV-iron administration has not been sufficiently evaluated in elective TJA.
This is a observational follow-up study among 6 Danish high volume surgical centres that has
recently introduced a standardized anaemia screening and treatment protocol for patients
with preoperative anaemia scheduled for total hip- or knee arthroplasty.
Patients with iron deficiency anaemia or anaemia of chronic inflammation receive infusion of
IV-iron (Monofer) 4 weeks prior to surgery as a part of the standard operating procedure on
the department.
The aim of this follow up study is to evaluate changes in Haemoglobin concentration,
transfusion rate and postoperative morbidity in this cohort.
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Observational Model: Cohort, Time Perspective: Prospective
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