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Anemia clinical trials

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NCT ID: NCT00661505 Completed - Anemia Clinical Trials

A Study of Intravenous Mircera in Hemodialysis Patients With Chronic Renal Anemia

Start date: May 14, 2008
Phase: Phase 3
Study type: Interventional

This single arm study will assess the efficacy, safety and tolerability of once-monthly administration of intravenous Mircera for the maintenance of hemoglobin levels in hemodialysis patients with chronic renal anemia. Patients will receive 4-weekly intravenous injections of Mircera, at a starting dose of 120, 200 or 360 micrograms. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.

NCT ID: NCT00661388 Completed - Anemia Clinical Trials

A Study of Monthly Subcutaneous Mircera for the Treatment of Chronic Renal Anemia in Predialysis Patients Not Treated With ESA.

Start date: August 2008
Phase: Phase 3
Study type: Interventional

This single arm study will assess the efficacy and safety of subcutaneous Mircera for the correction and maintenance of hemoglobin levels in predialysis patients with renal anemia who are not currently treated with ESA. Eligible patients will receive monthly subcutaneous injections of Mircera at an initial recommended dose of 1.2 micrograms/kg. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.

NCT ID: NCT00660933 Completed - Anemia Clinical Trials

Intravenous Iron Versus Oral Iron for Severe Postpartum Anemia

Start date: September 2005
Phase: Phase 4
Study type: Interventional

The aim of the study is to compare the effect of intravenous versus oral iron in women with severe postpartum anemia.

NCT ID: NCT00660023 Completed - Anemia Clinical Trials

A Study of Intravenous Mircera in Participants With Chronic Renal Anemia Who Are on Dialysis

Start date: August 2008
Phase: Phase 3
Study type: Interventional

This single-arm study will assess the efficacy and safety of monthly administration of intravenous methoxy polyethylene glycol-epoetin beta (CERA/Mircera) for the maintenance of hemoglobin (Hb) levels in participants on dialysis with chronic renal anemia in routine clinical practice in Hungary. Participants currently receiving maintenance treatment with intravenous epoetin or darbepoetin will receive monthly injections of Mircera, with the starting dose derived from the erythropoiesis-stimulating agent (ESA) dose they had been receiving.

NCT ID: NCT00659061 Completed - Anemia Clinical Trials

Monitoring and Evaluation of Micronutrients (Sprinkles) Project

Sprinkles
Start date: August 2007
Phase: N/A
Study type: Interventional

The purpose of this study is 1) to evaluate the effectiveness in reducing anemia among children 6-24 months of age by providing daily micronutrient Sprinkles through the Government of Pakistan's Lady Health Worker program; 2) to assist in the monitoring the National Sprinkles Pilot Project.

NCT ID: NCT00655408 Completed - Anemia Clinical Trials

Iron-Deficiency Anemia in Infants in Two Weekly Programs

IDA
Start date: April 2003
Phase: N/A
Study type: Interventional

This work aims at establishing the effectiveness of weekly doses of ferrous sulfate administered by mothers compared with weekly supplements administered directly by healthcare professionals, to reducing anemia prevalence.

NCT ID: NCT00651573 Completed - Anemia Clinical Trials

Balancing Risk: Red Blood Cell Transfusion Strategies In Cardiac Surgery

Start date: March 2007
Phase: N/A
Study type: Interventional

The primary purpose of this study is to determine the best blood level to begin transfusing red blood cells in individuals undergoing cardiac surgery. The secondary aim is to determine the impact of red cell transfusion on health-related quality of life following surgery.

NCT ID: NCT00642967 Completed - Anemia Clinical Trials

A Study of Subcutaneous Mircera for the Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease Not on Dialysis

Start date: June 2008
Phase: Phase 3
Study type: Interventional

This single arm study will assess the efficacy and safety of monthly administration of subcutaneous methoxy polyethylene glycol-epoetin beta (Mircera) when administered for the maintenance of hemoglobin levels in participants with chronic renal anemia, not on dialysis. Participants currently receiving treatment with subcutaneous epoetin or darbepoetin alfa will receive monthly subcutaneous injections of methoxy polyethylene glycol-epoetin beta, with the starting dose (120 or 200 micrograms) calculated from the last weekly dose of epoetin beta or darbepoetin alfa previously administered.

NCT ID: NCT00642863 Completed - Clinical trials for Iron Deficiency Anemia

Brain and Behavior Depending on Timing of Iron Deficiency in Human Infants

Start date: April 2008
Phase: N/A
Study type: Interventional

It is common in many populations that babies develop iron deficiency or iron deficiency anemia (that is, too few healthy red blood cells due to lack of iron). This is due to rapid growth in infancy combined with limited sources of iron in the infant diet. The amount of iron the baby receives across the placenta during pregnancy is another important factor. This study focuses on infants who are born with less than the usual amount of iron in their bodies. The purposes of the study are to assess effects of lower iron at birth on infant behavior and development and to determine if providing iron supplements to such infants beginning at 6 weeks fosters healthier development. Another part of the study will determine the effects of iron deficiency anemia at different times during infant development.

NCT ID: NCT00642850 Completed - Anemia Clinical Trials

STABIL Study: National Study With Mircera for Maintenance of Hemoglobin Level in Dialysis Patients

Start date: November 2007
Phase: Phase 3
Study type: Interventional

This single arm study will assess the efficacy, safety and tolerability of once-monthly administration of intravenous Mircera for the maintenance of hemoglobin levels in dialysis patients with chronic renal anemia. Patients will receive monthly intravenous injections of Mircera, at a starting dose of 120, 200 or 360 micrograms, according to the dose of epoetin administered in the week preceding first study drug administration. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.