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Anemia clinical trials

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NCT ID: NCT00236938 Completed - Anemia Clinical Trials

Efficacy and Safety of Venofer (Iron Sucrose Injection USP) in Patients Receiving Peritoneal Dialysis

Start date: July 2002
Phase: Phase 3
Study type: Interventional

This is a open-label, prospective study comparing intravenous (IV) iron supplementation to standard care in anemic patents undergoing peritoneal dialysis.

NCT ID: NCT00236678 Terminated - Clinical trials for Rheumatoid Arthritis

Randomized, Double-blind, Placebo-controlled Study to Assess Fatigue in Patients With ACD Due to RA Receiving PROCRIT

Start date: July 2004
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to determine fatigue (tiredness) in subjects with chronic Rheumatoid Arthritis with chronic anemia. Fatigue in subjects who get PROCRIT will be compared to fatigue in subjects who get placebo (a medically inactive substance). The study will also evaluate hemoglobin levels (oxygen-carrying protein in red blood cells), safety, anemia related health concerns, vitality, arthritis related function and work productivity.

NCT ID: NCT00236405 Terminated - Anemia Clinical Trials

PROCRIT and Short-Term Outcomes in Orthopedic Surgery

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the effect of perioperative administration of PROCRIT to that of autologous blood donation on post-operative rehabilitation outcomes in patients undergoing unilateral knee surgery.

NCT ID: NCT00233597 Completed - Anemia Clinical Trials

Ferumoxytol Versus Oral Iron in the Treatment of Anemia in Hemodialysis Patients

Start date: August 2004
Phase: Phase 3
Study type: Interventional

The study will evaluate the safety and efficacy of a new intravenously administered iron drug to treat anemia in patients on hemodialysis.

NCT ID: NCT00229619 Completed - Anemia, Aplastic Clinical Trials

Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia

Start date: September 2005
Phase: Phase 2
Study type: Interventional

This study will test whether the immune-suppressing drug rituximab can increase blood counts and reduce the need for transfusions in patients with moderate aplastic anemia, pure red cell aplasia, or Diamond Blackfan anemia. These are rare and serious blood disorders in which the immune system turns against bone marrow cells, causing the bone marrow to stop producing red blood cells in patients with pure red cell aplasia and Diamond Blackfan anemia, and red blood cells, white blood cells and platelets in patients with aplastic anemia. Rituximab is a laboratory-made monoclonal antibody that recognizes and destroys white blood cells called lymphocytes that are responsible for destroying bone marrow cells in these diseases. The drug is currently approved by the Food and Drug Administration for treating patients with B-cell non-Hodgkin lymphoma, a disease of white blood cells.

NCT ID: NCT00228995 Terminated - Anemia Clinical Trials

A Phase II Study to Assess Changes in Physical Function in Elderly Patients With Chronic Anemia

Start date: June 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess changes in physical function in elderly patients (>= 65 years of age) with chronic anemia (Hb <= 11.0 g/dL) due to anemia of unknown cause and receiving weekly subcutaneous doses of Epoetin alfa (PROCRIT®) versus placebo.

NCT ID: NCT00228449 Completed - Anemia Clinical Trials

Peginesatide for Anemia in Chronic Hemodialysis Patients

Start date: July 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple intravenous doses of peginesatide in participants with chronic kidney disease (CKD) who are on hemodialysis.

NCT ID: NCT00228436 Completed - Anemia Clinical Trials

Safety, PD & PK of Multiple Doses of Peginesatide for Anemia in Chronic Kidney Disease Patients

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study was to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple subcutaneous injections of peginesatide in participants with chronic kidney disease (CKD) not on dialysis who had not received erythropoiesis stimulating agent (ESA) treatment.

NCT ID: NCT00224068 Completed - Anemia Clinical Trials

Effect of Iron Therapy as an Adjunct to Epoetin Alfa in the Anemia of Cancer Chemotherapy

Start date: May 2002
Phase: Phase 4
Study type: Interventional

This study evaluates the safety and efficacy of Ferrlecit® (ferric gluconate; a form of intravenous iron) or ferrous sulfate (a form of oral iron) in improving the response to epoetin alfa among anemic cancer patients receiving chemotherapy.

NCT ID: NCT00224003 Completed - Anemia Clinical Trials

Study of the Safety and Efficacy of Ferrlecit® Maintenance Dosing in Pediatric Hemodialysis Patients

Start date: April 2003
Phase: Phase 4
Study type: Interventional

A phase 4 clinical investigation in iron-replete pediatric hemodialysis patients, whose legal guardian had provided signed informed consent, and who had satisfied the inclusion and exclusion criteria of the study.