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A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell Clinical Trial

Official title:
An Open Label Phase 2a Ascending Multiple Dose Safety, Efficacy, and Pharmacokinetic Study of HBI-002 Carbon Monoxide Oral Liquid Drug Product in Adolescents and Adults With Sickle Cell Disease.

Clinical Trial Summary

This is a multi-center, open label Phase 2a clinical trial in subjects with sickle cell disease to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of HBI-002, an orally administered liquid containing carbon monoxide (CO), with doses daily for 14 days.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06144749
Study type Interventional
Source Hillhurst Biopharmaceuticals, Inc.
Contact Andrew Gomperts
Phone 858 232 9495
Email hillhurstinfo@hillhurstbio.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date May 1, 2024
Completion date December 1, 2024
View Details
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