Clinical Trials Logo
  1. Home
  2. Anemia, Iron Deficiency
  3. NCT02570854

A Two-part Single- and Repeat-dose Study of CSJ137 in Anemic Chronic Hemodialysis Patients

Anemia, Iron-Deficiency Clinical Trial

Official title:
A First-in-human, Two-part (Open Label, and Randomized/Double Blind/Placebo Controlled), Single- and Repeat-dose Study of CSJ137 in Erythropoietin-treated Chronic Hemodialysis Patients With Functional Iron-deficiency Anemia

Clinical Trial Summary

The study will assess the safety, tolerability and efficacy of CSJ137 in chronic hemodialysis patients. It is hypothesized that treatment with CSJ137 may improve the level of hemoglobin in patients on chronic hemodialysis with iron-restricted anemia while reducing the need for dosing with erythropoietin and intravenous iron in these patients.

Clinical Trial Description

This posting discloses information about Part 1 of CCSJ137X2201. Another part, Part 2, of this trial was planned for conduct subsequent to the initiation of Part 1 and would have a different design than Part 1. However, due to internal strategic non-safety related decision, Part 2 is not going to be conducted and the trial will be terminated after Part 1. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02570854
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 1
Start date September 22, 2015
Completion date May 13, 2020
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT03516734 - Iron-fortified Lentils to Improve Iron (Fe) Status in Bangladesh N/A
Completed NCT02887963 - Epidemiological Study of Iron Deficiency and Iron Deficiency Anemia in Chinese Pregnant Women N/A
Completed NCT00534144 - Comparison Between Effects of Two Iron Preparations on Protein in the Urine Phase 1
Completed NCT00224081 - DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin) Phase 4
Recruiting NCT02999217 - Intravenous Iron for Correction of Anaemia After Colorectal Surgery Phase 4
Recruiting NCT04351607 - Preoperative Supplementation of Sucrosomal Iron as Hematopoietic Support. N/A
Completed NCT04163406 - The Effect of Human Milk Oligosaccharides and Galacto-oligosaccharides on Iron Absorption in Kenyan Infants N/A
Completed NCT02365103 - Tea Consumption and Iron Bioavailability in Women Using a Stable Isotope N/A
Completed NCT00536666 - A Study of Iron Oligosaccharide in Chronic Kidney Disease Patients Phase 3
Completed NCT02310607 - Non-invasive Optical Detection of Iron Deficiency N/A
Completed NCT01755455 - Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis N/A
Terminated NCT00929409 - Controlled Randomised Trial of Ferric Carboxymaltose and Oral Iron to Treat Postpartum Anemia Phase 2/Phase 3
Completed NCT00354692 - Effect of Two Iron Preparations on Protein in the Urine Phase 4
Recruiting NCT05628896 - Efficacy of a Preoperative Anaemia Clinic in Patients Undergoing Elective Abdominal Surgery
Completed NCT02892461 - Effect of Umbilical Cord Milking on Iron Related Health Outcomes for Cesarean-Delivered Infants N/A
Completed NCT02905539 - A Study Comparing the Iron Substitution With the Medicinal Products Ferinject or Monofer Phase 4
Not yet recruiting NCT01840384 - Efficacy Study of Multiple Micro Nutrients Supplementation N/A
Recruiting NCT00125996 - Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure Phase 1/Phase 2
Not yet recruiting NCT04975074 - Iron Deficiency Anemia in Twin Pregnancies Phase 4
Completed NCT03565354 - Efficacy of Preoperative Intravenous Iron in Anaemic Colorectal Cancer Surgical Patients Phase 3