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Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of CAR T cell treatment targeting CD7 in patients with relapsed or refractory CD7 positive T-cell hematological maliganacies


Clinical Trial Description

This study is single-armed,open lable,dose escalation clinical trial.The main purpose is to evaluate the safety and efficacy of anti-CD7 CAR-T cells in relapsed/refractory patients with CD7 positive T cell malignancies,including T lymphoblastic lymphoma/leukemia ,T-cell non-Hodgkin lymphoma(peripheral T cell lymphoma,NOS,angioimmunoblastic T cell lymphoma and anaplastic large cell lymphoma).There will be three CAR T cell dose groups:0.5*10^6 cells per kilogram of body weight;1*10^6 cells per kilogram of body weight,2 *10^6 ells per kilogram of body weight. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05290155
Study type Interventional
Source Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Contact Xianmin G Song, MD
Phone 02163240090
Email shongxm@139.com
Status Recruiting
Phase Phase 1
Start date May 4, 2022
Completion date November 1, 2024

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