Serratus Plane Block Versus Serratus Plane Block Plus Parasternal Block Combination for Breast Surgery

Analgesia Clinical Trial

Official title:

Serratus Plane Block Versus Serratus Plane Block Plus Parasternal Block on Postoperative Opioid Consumption and Dermatomal Analyses for Breast Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05911373
• Other study ID #: ataunibreastanalgesia
• Status: Completed
• Phase: N/A
• Start date: June 21, 2023
• Est. completion date: January 15, 2024

Study information

• Verified date: March 2024
• Source: Ataturk University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Mastectomy is a technique often used in breast cancer surgery. Patients experience moderate to severe pain postoperatively after this procedure. Various plane blocks, NSAIDs, and opioid analgesics can be administered to these patients as components of multimodal analgesia. In the the study, the investigators aimed to evaluate the analgesic effects of the serratus plane block, the parasternal block added to the serratus plane block, and the dermatomal differences.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 64
• Est. completion date: January 15, 2024
• Est. primary completion date: January 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

1. American Society of Anesthesiologist's physiologic state I-III patients

2. To undergo Mastectomy Surgery

3. Being between the ages of 18-65 years

Exclusion Criteria:

• Having a known heart, kidney, liver or hematological disease

• Having a history of peptic ulcer, gastrointestinal bleeding, allergy, chronic pain

• Routine analgesic use and history of analgesic use in the last 24 hours

• Not willing to participate in the study

• Uncooperative patients who have coagulopathy or use anticoagulant drugs

• To be allergic to one of the drugs to be used

Related Conditions & MeSH terms

• Analgesia
• Breast Neoplasms
• Cancer, Breast

Intervention

Other:
• group serratus plan block
preoperativelly, Superficial Serratus Block performed with 30 ml %0.25 Bupivacaine and Parasternal Block performed with 10 ml saline
• group serratus and parasternal plan block
preoperativelly, Superficial Serratus Block performed with 30 ml %0.25 Bupivacaine and Parasternal Block performed with 10 ml %0.25 Bupivacaine

Locations

Country	Name	City	State
Turkey	Ali Ahiskalioglu	Erzurum

Sponsors (1)

Lead Sponsor	Collaborator
Ataturk University

Country where clinical trial is conducted

Turkey, 

References & Publications (2)

Hu NQ, He QQ, Qian L, Zhu JH. Efficacy of Ultrasound-Guided Serratus Anterior Plane Block for Postoperative Analgesia in Patients Undergoing Breast Surgery: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Pain Res Manag. 2021 Oct 25;2021:7849623. doi: 10.1155/2021/7849623. eCollection 2021. — View Citation

Piraccini E, Biondi G, Corso RM, Maitan S. The use of rhomboid intercostal block, parasternal block and erector spinae plane block for breast surgery. J Clin Anesth. 2020 Feb;59:10. doi: 10.1016/j.jclinane.2019.06.004. Epub 2019 Jun 6. No abstract available. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative opioid consumption	First 24 hours total fentanyl consumption with patient controlled analgesia	first 24 hours
Secondary	Visual analog pain score	Post operative pain will be evaluated with a Visual Analogue Scale (between 0-10; 0: no pain, 10:worst pain) score	First 24 hours
Secondary	Sensory Assessment	Sensory Assessment will be performed on patients following the block procedure with pinprick test.	24 hours