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Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery

Analgesia Clinical Trial

Official title:
Comparison of the Analgesic Effects of Tramadol, Pethidine and Morphine Under Erector Spinae Plane (ESP) Block in the Treatment of Pain After Elective Thoracic Surgery

Clinical Trial Summary

Comparison of analgesic effects of tramadol, aldolan and morphine under thoracic surgery

Clinical Trial Description

Thoracotomy is one of the most painful surgical procedures known, and severe pain is encountered in 21-67% of patients after thoracotomy. The most important causes of this pain arise from the bone structures of the thoracic wall, damage to the costal joint junctions, stretching of the ligaments, rib fractures, and damage to the intercostal nerve and major muscles. Another factor that causes pain after thoracotomy is the chest tubes placed in the thorax to provide drainage (1). As a result of this pain caused by loss of tissue and pulmonary reserve, effective coughing and decreased chest expansion can lead to serious complications such as atelectasis, ventilation/perfusion mismatch, hypoxemia, immobilization, thromboembolism and infection. These complications are associated with increased morbidity and mortality in thoracic surgery (2). Ensuring pain management in patients undergoing thoracotomy is important in terms of reducing postoperative complications, ensuring early mobilization and increasing patient comfort. Since there is no single source that causes pain after thoracotomy, pain must be controlled at all levels. For this reason, a multimodal approach using pharmacological and non-pharmacological techniques is preferred in analgesia after thoracotomy. This approach reduces drug side effects along with the consumption of analgesics. Opioids and nonsteroidal anti-inflammatory drugs are used in pharmacological analgesia. In our study, the investigators aim to compare the effects of tramadol, pethidine and morphine using intravenous patient-controlled analgesia in the treatment of postoperative pain in elective thoracic surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06172920
Study type Interventional
Source Baskent University
Contact Begum N Gokdemir, MD
Phone 03122036868
Email begokdemir@yahoo.com
Status Not yet recruiting
Phase Phase 4
Start date December 31, 2023
Completion date December 9, 2024
View Details
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