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Clinical Trial Summary

2QR-complex is a patented molecule extracted from Aloe vera barbadensis leaves that blocks the adhesion of pathogenic microbes to human epithelial cells and tissues [9]. Anti-adhesion therapy such as 2QR-complex has been suggested as an alternative to antibiotics in the treatment of bacterial infections. 2QR-complex based products have already shown comparable efficacy to antibiotics in treating mucosal infections such as bacterial vaginosis.

In the present study we aim to assess the efficacy of 2QR-complex in pain relief and promotion of anal wound healing after anal surgery. We presumed that anal discomfort and prolonged healing after surgery for anal fissure, fistula, and hemorrhoids may in part be due to contamination of the wound with fecal bacteria that colonize at the surgical site. Therefore, we assumed that the use of topical anti-adhesive 2QR-complex-based product may serve to minimize this negative impact on wound healing.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT04275596
Study type Interventional
Source Mansoura University
Contact Sameh H Emile, M.D.
Phone +201006267150
Email sameh200@hotmail.com
Status Recruiting
Phase Phase 3
Start date February 10, 2020
Completion date May 30, 2021