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Relationship Between Neurological Disability and Visual Impairment in Patients With ALS or Friedreich's Ataxia

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
Relationship Between Neurological Disability and Visual Impairment in Patients With ALS or Friedreich's Ataxia

Clinical Trial Summary

The aim of this study is to obtain an early biomarker of amyotrophic lateral sclerosis and Friedreich's Ataxia which allows to diagnose the disease in an initial stage and to follow up the patient with optic coherence tomography, a fast, non-invasive and comfortable method

Clinical Trial Description

All patients will be asked about their data and their general medical history, and will be underwent on one hand, a complete neurological examination including the degree of neurological impairment quantified according to the functional rating scale of ALS (ALSFRS-r) or Scale for the assessment and rating of ataxia (SARA); On the other hand, they will have a complete ophthalmological examination too, including the patient's graduation, pupillary and ocular motility examination, biomicroscopy, Goldman tonometry and fundus exam. Patients will be performed too a conventional automated Humprey perimetry, color test (Farnsworth-Munsell 28 Hue Color Vision Test) and finally an optical coherence tomography (OCT) in order to see possible anatomical alterations in both macula and optic nerve. The follow-up of these explorations will be repeated in all cases at 6 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03285204
Study type Observational
Source Hospital General Universitario Gregorio Marañon
Contact Pilar Rojas, MD
Phone +34616042758
Email pilar.rojas.lozano@gmail.com
Status Recruiting
Phase
Start date July 2015
Completion date February 2020
View Details
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