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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT00033072
Other study ID # NIDA-CTO-0004-1
Secondary ID
Status Active, not recruiting
Phase Phase 1
First received April 5, 2002
Last updated January 10, 2017
Start date September 2001
Est. completion date October 2002

Study information

Verified date November 2003
Source National Institute on Drug Abuse (NIDA)
Contact n/a
Is FDA regulated No
Health authority United States: Food and Drug Administration
Study type Interventional

Clinical Trial Summary

The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral selegiline.


Description:

To determine the safety of the selegiline concurrent with d-methamphetamine challenges of 15mg & 30mg i.v. with the focus being on cardiovascular responses (HR,BP) to the i.v. methamphetamine challenges. This is a randomized, single-blind, placebo-controlled, two-arm study design to evaluate the safety of selegiline treatment, compared to placebo treatment, concurrent with i.v. methamphetamine challenges.


Other known NCT identifiers
  • NCT00024882

Recruitment information / eligibility

Status Active, not recruiting
Enrollment 16
Est. completion date October 2002
Est. primary completion date
Accepts healthy volunteers No
Gender All
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria:

- Volunteers who meet DSM-4 criteria for methamphetamine abuse or dependence; non-treatment seeking individuals

- Be able to verbalize understanding of consent form; provide written informed consent

Exclusion Criteria:

- Please contact site for more information

Study Design

Allocation: Randomized, Masking: Single Blind, Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Drug:
Selegiline


Locations

Country Name City State
United States UCLA Integrated Substance Abuse Program Los Angeles California

Sponsors (1)

Lead Sponsor Collaborator
National Institute on Drug Abuse (NIDA)

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary safety of selegiline
Primary pharmacokinetic assessment
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