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Clinical Trial Summary

An open label multi centre study to assess the safety and efficacy of BST-236 in combination with venetoclax in adult patients unfit for standard therapy with newly diagnosed Acute Myeloid Leukemia (AML) Part 1 of the study will define the maximal tolerate dose of the combination treatment, while part 2 will expend the chosen dose, to assesses efficacy and safety of this combination. All patients will receive 2 induction courses with both BST-236 and venetoclax, responding patients will then be followed with up to 3 maintenance courses with BST-236 alone. Patients will be followed for 1 year in the study and additional 1 year in post study follow-up


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05503355
Study type Interventional
Source BioSight Ltd.
Contact
Status Recruiting
Phase Phase 1/Phase 2
Start date August 17, 2022
Completion date December 1, 2025

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