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Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery

Ambulatory Surgical Procedures Clinical Trial

Official title:
Efficacy of Different Doses of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery With Desoflurane Anesthesia

Clinical Trial Summary

Emergence agitation/delirium (EA/ED) is a common complication in pediatric surgery patients, which increases the risk of developing postoperative airway obstruction and respiratory depression. In infants, there is a high incidence of emergence agitation (EA) after desoflurane anesthesia. The aim of the present preliminary study was to determine the safety and efficacy of of intraoperative infusion of dexmedetomidine (DEX) that would prevent postoperative EA and ED in children undergoing day surgery with desoflurane anesthesia

Clinical Trial Description

subjects who underwent day surgery were stratified into two age groups as follows: low to 3 years group, and 3-12 years group. Then they were randomly assigned to receive one of six doses of intravenous dexmedetomidine: 0, 0.2, 0.4, 0.6, 0.8 ,1.0ug/kg before skin incision. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03262090
Study type Interventional
Source Guangzhou Women and Children's Medical Center
Contact
Status Completed
Phase N/A
Start date September 18, 2017
Completion date May 21, 2019
View Details
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