Acupuncture Treatment for Improving Alzheimer's Dementia

Alzheimer Disease Clinical Trial

Official title:

Clinical Trial to Measure Efficacy of Acupuncture Treatment for Alzheimer's Dementia as Measured by MOCA(Montreal Cognitive Assessment)

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT04064021
• Other study ID #: NS1
• Status: Withdrawn
• Phase: N/A
• Start date: January 1, 2025
• Est. completion date: March 31, 2027

Study information

• Verified date: October 2022
• Source: N & S Neurology Center, A Medical Group, Inc
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Evaluate cognitive improvement pre amd post acupuncture treatment in patients with probable alzheimer's dementia as measured by MOCA score and also per form A( measure of patient's personal information). Also caregiver input.

Description:

Patient's with diagnosis of probable mild to moderate AD will be enrolled in this study. Patient will undergo neurological examination including MOCA. Examiner will also fill out Form A at the time of initial evaluation. Patient will then undergo series of acupuncture treatments 2 per week for 6 weeks(12 acupuncture treatment). At end of this intervention patients will be reassessed using same testing(MOCA and form A) Data collected will be assessed via statistical analysis to see if there is any statistically significant improvement. Acupuncture points used in this trial will stay the same for all subjects and throughout the course. The points will be Si Shen Chong, ST36, 37, LV 2,3,6, GB 34, 39, Xia San Huang, LI 11, LI 4.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: March 31, 2027
• Est. primary completion date: December 31, 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years to 80 Years

Eligibility

Inclusion Criteria:

• Mild to moderate AD

Exclusion Criteria:

• Severe AD

Related Conditions & MeSH terms

• Alzheimer Disease
• Cognition Disorders
• Cognitive Deficits
• Cognitive Dysfunction
• Dementia

Intervention

Procedure:
• Acupunture
Patient will receive 12 acupuncture treatments over 6 weeks (2x per week)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
N & S Neurology Center, A Medical Group, Inc

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Improvement on Montreal Cognitive Assessment test of 5 points or more than baseline( total score is out of 30 points)	Subject will complete 3 MOCA assessment prior to study over 1 week time. Best score of three is used.; After study is complete subject will also undergo 3 MOCA assessment over 1 week immediately after study. Again best score is used.	12 weeks
Secondary	Improvement of Montreal Cognitive Assessment test by category than raw total score	performance on various subcategory will also be reviewed to see if one category improves over other category. (Example: Visual-spacial parameters improves over language)	12 weeks