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Clinical Trial Summary

This is a Phase 2 open label pilot study to evaluate the safety and efficacy of subcutaneously administered ELX-02 in patients with X-linked or autosomal recessive Alport Syndrome with Col4A5 and Col4A3/4 nonsense mutation. In total, up to 8 participants, with a minimum of 3 adults, will be enrolled in the trial. The study will be comprised of the following periods for each participant: - a Screening period of up to 6 weeks (42 days) - a total Treatment Period of 8 weeks (60 days) - a safety/efficacy Follow-up Period of 12 weeks (90 days) after the last treatment The Treatment Period will be a treatment of ELX-02 0.75 mg/kg SC QD for 8 weeks.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05448755
Study type Interventional
Source Eloxx Pharmaceuticals, Inc.
Contact Eloxx Pharmaceuticals
Phone +1(781) 577-5300
Email info@eloxxpharma.com
Status Recruiting
Phase Phase 2
Start date November 28, 2022
Completion date May 30, 2023

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