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Alopecia clinical trials

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NCT ID: NCT02591355 Completed - Clinical trials for Androgenetic Alopecia

Evaluate the Clinical Effectiveness of RegenKit Platelet-rich Plasma (PRP) in Androgenetic Alopecia Treatment

Start date: September 6, 2017
Phase: N/A
Study type: Interventional

Platelet rich plasma (PRP) therapy is a novel therapeutic modality that has seen broad applications for a number of medical indications including those in orthopedics, dentistry, and dermatology. In dermatology, its uses have included treatment of chronic wounds and facial rejuvenation. More recently, anecdotal reports have suggested some efficacy in the treatment of hair loss, but to the best of our knowledge, there has been only one published case series documenting its use for this indication.

NCT ID: NCT02561585 Completed - Alopecia Areata Clinical Trials

LEO 124249 Ointment in the Treatment of Alopecia Areata

Start date: January 2016
Phase: Phase 2
Study type: Interventional

This clinical trial attempts to investigate the efficacy and safety of LEO 124249 ointment in the treatment of alopecia areata and the molecular disease mechanism and biomarkers.

NCT ID: NCT02557074 Completed - Alopecia Areata Clinical Trials

TREg Activation in the Treatment of the PELADE (Alopecia Areata)

TreatPelade
Start date: December 15, 2015
Phase: Phase 3
Study type: Interventional

In a prospective pilot study the investigators showed that low doses of IL2 could be beneficial for severe AA inducing a long lasting regrowth in 4 out of the 5 patients treated. The objective of this study is to compare the long term efficacy of low doses of IL2 versus placebo in a multicenter prospective randomized double blind study.

NCT ID: NCT02553330 Terminated - Alopecia Areata Clinical Trials

A Study With Ruxolitinib Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)

Start date: November 18, 2015
Phase: Phase 2
Study type: Interventional

A phase 2 study to find out if the drug ruxolitinib Phosphate Cream is safe and has beneficial effects in people who have alopecia areata (partial or complete hair loss) when applied to the skin.

NCT ID: NCT02548689 Terminated - Alopecia Areata Clinical Trials

PAI-1 Expression in Non-scarring Hair Loss

Start date: July 2015
Phase:
Study type: Observational

This study will investigate whether subjects who suffer from hair loss have increased levels of PAI-1 compared to age-matched control subjects. The level of PAI-1 expression will be determined in subjects without hair loss and in subjects with non-scarring hair loss, including androgenetic alopecia, telogen effluvium and alopecia areata.

NCT ID: NCT02530177 Active, not recruiting - Clinical trials for Non-Metastatic Breast Cancer

Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

Start date: August 19, 2015
Phase:
Study type: Observational

The purpose of this study is to see how many patients develop hair, skin and nail changes due to cancer treatments. The investigators would like to study the clinical factors, genetic markers, and impact on patients' health-related quality of life to learn more about who is at greater risk. We trust that the study will improve our understanding of how cancer patients feel about their skin, hair, and nail conditions. This information will help us determine the burden on breast cancer patients and survivors. It will also help us learn how to prevent these conditions and it may improve the way we treat them and counsel patients.

NCT ID: NCT02528552 Active, not recruiting - Clinical trials for Androgenetic Alopecia

Treatment of Androgenetic Alopecia in Males With Theradomeā„¢ LH80 PRO

Start date: August 2015
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized double-blind, multi-center study to evaluate the efficacy of low level laser therapy over-the-counter at home device Theradome LH80 PRO, compared to SHAM for promoting hair growth in males diagnosed with androgenetic alopecia, and a usability study to assess subject ability to self-assess hair loss and understanding use of the device.

NCT ID: NCT02503852 Completed - Clinical trials for Alopecia, Androgenetic

STYLE -- A Trial of Cell Enriched Adipose For Androgenetic Alopecia

STYLE
Start date: November 2015
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the safety and feasibility of the Celution and Puregraft Systems in the processing and preparation of an autologous fat graft enriched with adipose-derived regenerative cells (ADRCs) in the treatment of early alopecia androgenetica.

NCT ID: NCT02503137 Completed - Clinical trials for Androgenetic Alopecia

A Study of SM04554 Applied Topically to the Scalp of Male Subjects With Androgenetic Alopecia Analyzed by Biopsy of the Scalp Prior To and Post Dosing

Start date: August 2015
Phase: Phase 2
Study type: Interventional

This study will assess the safety, tolerability, and efficacy of SM04554 at concentrations of 0.15% and 0.25%. Improved knowledge of the changes in hair counts and immunohistochemical analysis associated with androgenetic alopecia (AGA) before and after treatment with SM04554 and compared to placebo may lead to a greater understanding of the underlying mechanisms of action of SM04554.

NCT ID: NCT02494297 Completed - PCOS Clinical Trials

DUS on the Prescribing Indications for CPA/EE in 5 European Countries

Start date: March 6, 2015
Phase:
Study type: Observational

This study was designed to compile the reasons and specific indications for the prescription of Cyproterone Acetate combined with Ethinyl Estradiol by Health Care Providers. The primary objective of the study was to characterize the prescribing behaviors for Cyproterone Acetate combined with Ethinyl Estradiol in 5 European countries (Austria, Czech Republic, France, the Netherlands, and Spain), including: - prescription indications for Cyproterone Acetate combined with Ethinyl Estradiol - use of Cyproterone Acetate combined with Ethinyl Estradiol in accordance with the updated label - concomitant use of Cyproterone Acetate combined with Ethinyl Estradiol and combined hormonal contraceptives - second line treatment with Cyproterone Acetate combined with Ethinyl Estradiol for the indication acne