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NCT02293343 Clinical Trial

24 Hrs Histamine Profile in Healthy Persons and Patients With Food Intolerance

Allergy Clinical Trial

Official title:
24 Hrs Histamine Profile in Healthy Persons and Patients With Food Intolerance: Correlations Between Subjective Affliction and Measured Histamine Parameter

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02293343
Other study ID # Histamine profile 1
Secondary ID
Status Completed
Phase N/A
First received November 13, 2014
Last updated May 10, 2017
Start date October 2014
Est. completion date May 2017

Study information
Verified date May 2017
Source University of Erlangen-Nürnberg Medical School
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Over 24 hrs serum and plasma samples were collected every 3 hrs. With this a day histamine profile was created. 15 healthy persons with 20 patients with a high level of IgE in serum and 20 patients with afflictions but no high IgE level were compared. Measurment of histamine in plasma, urine and stool were realized. In addition to that Diaminoxidase, TNF alpha and IgE Antibodies were measured.

Recruitment information / eligibility
Status Completed
Enrollment 65
Est. completion date May 2017
Est. primary completion date May 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

- healthy subjects

- appropriate invalid persons

Exclusion Criteria:

- pregnant and weaning persons

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• blood profile

Locations
Country Name City State
Germany Universitätsklinikum Erlangen Erlangen

Sponsors (1)
Lead Sponsor Collaborator
University of Erlangen-Nürnberg Medical School

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Other TNF alpha 24 hrs
Other IgE 24 hrs
Primary Histamine 24 hrs
Secondary diaminoxidase 24 hrs
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