Allergic Rhinitis Clinical Trial
Official title:
Does Specific Immunotherapy Possess Immunomodulative Effects at the Bronchial Mucosa Level Among Adults With Atopic Diseases?
The purpose of this study is to evaluate the immunomodulatory effect of treatment of allergic rhinitis symptoms with specific immunotherapy by measurement of pulmonary inflammatory markers, and among others, exhaled nitric oxide.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | December 2008 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - Age 18-45 years old - Skin prick test or RAS test and physical examination conclude that the patient will have a beneficial effect from specific immunotherapy Exclusion Criteria: - Other diseases except atopic disease - Pregnancy |
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Denmark | Bispebjerg Hospital | Copenhagen |
Lead Sponsor | Collaborator |
---|---|
Bispebjerg Hospital |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Skin prick test | |||
Primary | Spirometry | |||
Primary | Methacholine provocation of the pulmonary system | |||
Primary | Exhaled nitric oxide | |||
Primary | Immunoglobulin E (IgE) status | |||
Primary | Sputum examination | |||
Primary | Condensation of exhaled air | |||
Secondary | Questionnaire |
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