Expanded Access Program for Tiratricol in Patients With Monocarboxylate Transporter 8 Deficiency

Allan-Herndon-Dudley Syndrome Clinical Trial

Official title: Expanded Access Program for Tiratricol in Patients With Monocarboxylate Transporter 8 Deficiency Also Known as Allan-Herndon-Dudley Syndrome (AHDS)

Status Available

Clinical Trial Summary

The goal of this program is to provide expanded access (i.e., before marketing authorization) to tiratricol as treatment for patients with monocarboxylate transporter 8 deficiency (MCT8 deficiency, also known as Allan-Herndon-Dudley syndrome [AHDS]), who in their Treating Physician's opinion, could benefit from tiratricol and meet the eligibility criteria.

Clinical Trial Description

This will be an open-label, single-arm, multi-center EAP, designed to provide treatment access in the US to tiratricol for eligible patients with MCT8 deficiency, also known as AHDS.

Patients will undergo clinical and safety assessments before tiratricol treatment initiation, during the titration phase and then at approximately 3-6 monthly intervals or more frequently if clinically indicated, following the initiation of tiratricol treatment and until treatment is completed or discontinued.

Adverse events (AEs) and serious adverse events (SAEs) will be recorded and reported as per FDA regulations. ;

Related Conditions & MeSH terms

• Allan-Herndon-Dudley Syndrome
• Mental Retardation, X-Linked
• Muscle Hypotonia
• Muscular Atrophy
• Syndrome

• NCT number: NCT05911399
• Study type: Expanded Access
• Source: Rare Thyroid Therapeutics International AB
• Contact: AnovoRx
• Phone: +1-866-669-5659
• Email: EgetisEAP@anovorx.com
• Status: Available