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Topiramate for Alcohol and Cocaine Dependence — TOP2  

Alcoholism Clinical Trial

Official title:
A Phase II, Randomized, Double-blind, Placebo-Controlled, Pilot Trial of Topiramate for Alcohol and Comorbid Cocaine Dependence

Clinical Trial Summary

The primary purpose of this study is to test the effectiveness of topiramate for the treatment of combined alcohol and cocaine dependence. Topiramate is approved for the treatment of seizures. It has not been proven to be effective for the treatment of alcohol or cocaine dependence.

Clinical Trial Description

The purpose of this study is to evaluate the efficacy of 300 mg/day of topiramate for the treatment of 200 treatment-seeking alcohol dependent outpatients with comorbid cocaine dependence in a double-blind, placebo-controlled 14-week trial, with a 6-month follow-up (3 months after completing medications). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00167245
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase Phase 2
Start date September 2004
Completion date June 2010
View Details
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