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NCT02777840 Clinical Trial

High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients

Airway Morbidity Clinical Trial

— THRIVE/RSI 1  

Official title:
High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02777840
Other study ID # 15/LO/0277
Secondary ID
Status Recruiting
Phase N/A
First received May 13, 2016
Last updated October 3, 2017
Start date March 2015
Est. completion date March 2018

Study information
Verified date October 2017
Source St George's, University of London
Contact Lucy Parker
Phone 0208 266 6397
Email lparker@sgul.ac.uk
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

High flow oxygen results in better oxygenation in emergency cases needing rapid sequence induction for anaesthesia. Secondary outcome measure is time for any desaturation.

Description:

The investigators intend to do the study using high flow oxygen for all emergency cases needing rapid sequence induction. As part of the study the Investigators will measure the oxygen levels in the blood gas sample of the patient and the heart rate of anesthetist in charge of the airway management. After the airway is secured the time for desaturation will be noted.

Recruitment information / eligibility
Status Recruiting
Enrollment 80
Est. completion date March 2018
Est. primary completion date March 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 16 Years and older
Eligibility Inclusion Criteria:

- Emergency patients needing rapid sequence induction for surgery

- = 16 years

- Able to give consent

Exclusion Criteria:

- Patients age under 16 years

- Inability to give consent

- Severe respiratory disease

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• face mask oxygen
oxygen given by face mask as per routine practice
• High flow oxygen
High flow oxygen given via optiflo machine / device

Locations
Country Name City State
United Kingdom St Georges Hospital NHS Trust London

Sponsors (1)
Lead Sponsor Collaborator
St George's, University of London

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary Oxygen levels in blood gas sample Oxygen levels in blood gas sample after the airway is secured intraoperative
Secondary time to desaturation after airway is secured time will be noted for oxygen levels to fall to 92% before the ventilation is started. intraoperative or 10 minutes after intubation
Secondary heart rate of anaesthetist performing the intubation During the process of induction of anaesthesia and intubation upto 5 minutes post intubation
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