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Effect of Encapsulated vs Free Probiotic on Brain Function

Aging Clinical Trial

Official title:
Comparing the Efficacy of Micro-encapsulated Lactocaseibacillus Rhamnosus vs Free Probiotic in Powder to Affect Brain Connectivity

Clinical Trial Summary

Aging is associated with changes in a wide variety of brain networks, including the default mode, saliency attention, and visual networks. Furthermore, current research suggests that a relationship exists between functional connectivity at rest and cognition. Lactocaseibacillus rhamnosus is an ideal strain for the intervention, as it has been show to affect the gut-brain axis, brain function, and behavior. Therefore, the investigators plan to assess resting state functional magnetic resonance imaging (fMRI) to compare changes in brain connectivity between the groups receiving the encapsulate and non-encapsulated Lactocaseibacillus rhamnosus supplements.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05801042
Study type Interventional
Source Örebro University, Sweden
Contact
Status Active, not recruiting
Phase N/A
Start date February 7, 2023
Completion date June 30, 2024
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