Aging Clinical Trial
Official title:
Study of the Feature of Intestinal Microbiota and Its Role in Healthy Aging in Southern Chinese From a Longevity County, Yongfu
This study is an observational study designed to adopt a cross-sectional study design. In the
context of China's longevity town (East Asian population), Yongfu, Guangxi, the background of
non-medical care and antibiotic use was explored, and the intestinal microecological balance
increased with age and natural health. Longevity relationship. This study was completed using
a household survey. Through routine clinical examinations and analysis of biochemical
laboratory indicators, at the same time, a questionnaire for ADL(activities of daily living),
cognitive function, and related elderly information was carried out on the elderly to
comprehensively provide health information for each elderly. Based on the remaining stool
samples and serum samples, the second-generation sequencing technology and other omics-based
technologies were explored. No additional collection of human specimens and information is
involved.
In addition, this study also hopes to explore the transmission rules of age-related bacteria
in long-lived families, and the relationship with health phenotypes such as blood sugar,
blood lipids, and cognitive function. Potential impact. In summary, this study will provide
data support for exploring the relationship between healthy longevity and intestinal
microecological balance based on the characteristic population of the longevity hometown.
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