Aging Clinical Trial
Official title:
Effects of Low or High Amounts of Dietary Protein and Resistance Training on Community-dwelling Older Adults: a Randomized Controlled Trial
The aim of this randomized, observer-blind, controlled intervention study with parallel
groups is to study the effect of resistance training (2x/week for 8 weeks) with and without
different goals of protein intake on muscle strength, function and mass, oxidative stress
parameters and the immune system in community dwelling persons.
Participants (n = 137) will be community-dwelling older adults. After a pre-participation
screening participants will be distributed randomly but stratified by sex and age to one of
the 3 groups (low protein + strength training, high protein + strength training, low protein
and no strength training(=control)). Study participants are eligible if they are male or
female with an age between 65 and 85 years and if their cognitive status as well as their
physical fitness level allows to participate at the strength training sessions. Exclusion
criteria comprise chronic diseases which contraindicate the training sessions, serious
cardiovascular disease, diabetic retinopathy and manifest osteoporosis, a frailty index at or
above 3, medication with anticoagulants or cortisone drugs and also regular strength training
during the last six months.
Primary outcome measure is the change in the Chair Stand Test. Secondary outcome measures
comprise anthropometric data, functional performance tests, immunological and oxidative
stress parameters, microbiota, metabolomics, proteomics and the nutritional status.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Recruiting |
NCT06032065 -
Sequential Multiple Assessment Randomized Trial of Exercise for PAD: SMART Exercise for PAD (SMART PAD)
|
Phase 3 | |
| Completed |
NCT05293730 -
Trial of the Impact of the Electronic Frailty Integrated With Social Needs
|
N/A | |
| Recruiting |
NCT03932162 -
Gene Expression Changes In Young and Geriatric Skin
|
Early Phase 1 | |
| Completed |
NCT04064528 -
Effects of Age on Amino Acid Delivery to Tendon
|
N/A | |
| Completed |
NCT03366129 -
Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke
|
||
| Completed |
NCT06029920 -
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
|
N/A | |
| Recruiting |
NCT05566938 -
Study to Design a Precision Nutrition Strategy at a Group Level in the Elderly
|
N/A | |
| Recruiting |
NCT05543980 -
Leg Heat Therapy in Elderly Individuals
|
Phase 2 | |
| Completed |
NCT04894929 -
Comprehensive Geriatric Assessment in the Monitoring of Functional Improvement
|
N/A | |
| Not yet recruiting |
NCT06071130 -
Emotion, Aging, and Decision Making
|
N/A | |
| Enrolling by invitation |
NCT04641663 -
Multi-target Dietary Supplement Tolerability in an Aging Population (MTDSST)
|
N/A | |
| Completed |
NCT04088006 -
The Evaluation of Efficacy and Safety of Hyaluronic Acid Injection on Skin Moisturization and Elasticity
|
N/A | |
| Completed |
NCT03695081 -
Patient Pathway Pharmacist - Optimal Drug-related Care
|
N/A | |
| Recruiting |
NCT05424263 -
Acetate and Age-associated Arterial Dysfunction
|
Phase 2 | |
| Completed |
NCT05601713 -
Mitigating Heat-induced Physiological Strain and Discomfort in Older Adults Via Lower Limb Immersion and Neck Cooling
|
N/A | |
| Completed |
NCT04551339 -
Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19
|
N/A | |
| Recruiting |
NCT04997577 -
Speech Perception and High Cognitive Demand
|
N/A | |
| Completed |
NCT05922475 -
Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
|
N/A | |
| Completed |
NCT04015479 -
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
|
N/A |