A Prospective Cohort Study of Aged People for Chronic Diseases

Aging Clinical Trial

— HAPPY  

Official title:

A Hospital-based Prospective Cohort Study With Aged People to Elucidate Predictive Factors Including Muscle and Fat Mass for Chronic Diseases and Mortality

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02640872
• Other study ID #: SNUBH-HAPPY Cohort
• Status: Completed
• Start date: July 2015
• Est. completion date: March 15, 2021

Study information

• Verified date: March 2021
• Source: Seoul National University Bundang Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.

Description:

This study is a hospital-based, prospective cohort study to elucidate the predictive factors among anthropometric and biochemical parameters and body composition information for chronic diseases including diabetes mellitus, myocardial infarction, stroke, osteoporosis, fracture, and cognitive dysfunction, and mortality in elderly persons aged 60 years and older.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1000
• Est. completion date: March 15, 2021
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Aged 60 years and older

• Capable of communication with the research team

• Provided written informed consent

Exclusion Criteria:

• Age < 60 years

• active malignancy

• uncompensated liver cirrhosis

• ESRD

• severe cognitive impairment which cannot communicate with the research term

Related Conditions & MeSH terms

• Aging
• Chronic Disease
• Sarcopenia

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Bundang Hospital	Seongnam	Gyeonggi

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Bundang Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Alll cause mortality		9 years
Secondary	Cardiometabolic mortality		9 years
Secondary	Incidence of major adverse cardiac event including nonfatal myocardial infarction, nonfatal stroke, and unstable angina		9 years
Secondary	Incidence of frailty defined by the Korean Fraility Index		9 years
Secondary	Incidence of osteoporotic fracture		9 years
Secondary	Incidence of cognitive dysfunction measured by minimental status examination		9 years
Secondary	Development of sarcopenia defined by the Foundation for the National Institutes of Health (FNIH) criteria		9 years