Aging Clinical Trial
Official title:
The Impact of Piano Training on Cognitive Performance and Psychosocial Well-Being in Older Adults
This project evaluates the effects of piano training and computerized cognitive training on cognitive performance in healthy older adults compared to controls. The project is intended for healthy older adults (60-80 years) with little to no previous musical training (less than three years of prior musical training or cognitive training and not currently engaged in music reading or musical performance, less than 10 hours of previous cognitive training). Investigators anticipate that musical engagement will serve as an enjoyable cognitive intervention for older adults. Investigators believe that piano training will enhance cognitive performance on executive functions essential for maintaining independence in older adulthood. Learning a musical instrument, while challenging, will improve self-efficacy, mood, and qualtiy of life. Participants engaged in piano training will demonstrate reduced cortisol levels and increased immune function responses. Investigators predict that adults enrolled in computerized cognitive training will demonstrate enhanced memory, working memory and self-efficacy post-training.
The project purpose is to scientifically examine the benefits of piano training as compared
to computer cognitive training and no treatment controls on cognitive (processing speed,
task-switching, verbal fluency, verbal memory, and working memory), psychosocial (mood,
self-efficacy, and quality of life), and physiological variables (biomarkers) in healthy
older adult participants in a randomized clinical trial design.
Participants: Ninety community dwelling older adults will be recruited from the community.
Criteria for enrollment are: between the ages of 60-80, native English speakers, not
currently taking medications affecting memory performance, have no pre-existing cognitive
impairment or neurological disorders, (as indicated by the Telephone Interview for Cognitive
Status > 30), no moderate to severe depression (as indicated by the Geriatric Depression
Scale), no difficulty with hand movements, less than three years of prior musical training,
not currently engaged in music reading or musical performance, and less than ten hours of
prior computer brain training experience. Participants will be randomly assigned to one of
three groups stratified by intelligence and gender: piano instruction, computerized cognitive
training or a no treatment control group. Informed written consent will be obtained in
accordance with the Institutional Review Board.
Procedure: Participants will be tested in three visits: pre-training, immediately
post-training, and three months follow-up. Those randomized to piano training or computerized
cognitive training will complete their assigned training between pre-training and
post-training visits. Measures of music aptitude and intelligence will be administered at the
pre-training visit. These factors can influence cognitive performance. Any significant
differences at baseline between the three assigned groups will be statistically controlled
for in the analyses. Standardized cognitive measures will be used to examine processing
speed, task-switching, verbal fluency, verbal memory, and working memory at each visit.
Psychosocial outcomes (mood, self-efficacy, and quality of life) and physiological biomarkers
will also be evaluated at each visit.
The goal for both interventions will be to complete 48 hours of group training over a four
month period (16 weeks). Sixty participants (30 piano training; 30 auditory computer
training) will be asked to attend three hours of training each week. Thirty participants will
serve in the no treatment control group. Piano training will consist of basic piano
technique, dexterity exercises, piano literature, and music theory. Participants will be
expected to perform all major scales, repertoire from the Alfred All-in-One Method, and
complete weekly theory assignments. Each class session is structured as a cognitive
intervention that focuses upon review of materials (15-20 min), and the remaining portion of
the class focuses upon learning new skills and concepts. Computerized cognitive training
involves computerized perceptual practice exercises that vary in difficulty ranging from
basic auditory processing speed to application through memory exercises. Within each
exercise, the stimuli (i.e., tones, speech sounds, words, sentences) become less
discriminable and speed of presentation increases (making the exercises more difficult) as
performance improves. The Brain Fitness training program with working memory exercises will
be used.
Data source(s). Data will consist of a series of standardized cognitive, psychosocial, and
neurophysiological measures administered at three time points: pre-training, post-training,
and at a three month follow-up. All standardized measures have been previously used to assess
the efficacy of cognitive training approaches and demonstrate good psychometric properties.
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