Effects of Inspiratory Muscle Training in Elders

Aging Clinical Trial

Official title:

Respiratory Muscle Training in the Elderly: a Strategy for Preservation of Inspiratory and Expiratory Pressures Impacting on Mobility and Thickness of the Diaphragm.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01791010
• Other study ID #: IMT in elders
• Status: Completed
• Phase: N/A
• First received: February 6, 2013
• Last updated: February 9, 2013
• Start date: January 2012
• Est. completion date: December 2012

Study information

• Verified date: February 2013
• Source: Universidade Federal de Pernambuco
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Aging causes anatomical and physiological changes in the respiratory system and respiratory muscle strength with decline in its maximum function. This study aimed to evaluate the effects of inspiratory muscle training on respiratory muscle strength, thickness of the diaphragm and diaphragmatic mobility in older women. The investigators' hypothesis is that inspiratory muscle training improves respiratory muscle strength, the thickness of the diaphragm and diaphragmatic mobility in older women.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 22
• Est. completion date: December 2012
• Est. primary completion date: December 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 60 Years to 80 Years

Eligibility

Inclusion Criteria:

Elderly women are able to walk without aid and cognitive integrity.

Exclusion Criteria:

• Participation in other training or rehabilitation protocol;

• Contraindication or difficult to perform the evaluation;

• Difficulty adapting or adherence in training protocol;

• Smoking;

• Hemodynamic instability;

• Degenerative neuromuscular disease;

• Pulmonary comorbidities;

• Heart disease;

• Users of drugs that interfere in bone metabolism or muscle strength.

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Aging
• Muscular Atrophy
• Sensitivity Training Groups

Intervention

Other:
• Inspiratory muscle training

• Training sham
Conducting fake training with the aim of blind the control group

Locations

Country	Name	City	State
Brazil	Federal University of Pernambuco	Recife	Pernambuco

Sponsors (1)

Lead Sponsor	Collaborator
Universidade Federal de Pernambuco

Country where clinical trial is conducted

Brazil, 

References & Publications (3)

Enright SJ, Unnithan VB, Heward C, Withnall L, Davies DH. Effect of high-intensity inspiratory muscle training on lung volumes, diaphragm thickness, and exercise capacity in subjects who are healthy. Phys Ther. 2006 Mar;86(3):345-54. — View Citation

Testa A, Soldati G, Giannuzzi R, Berardi S, Portale G, Gentiloni Silveri N. Ultrasound M-mode assessment of diaphragmatic kinetics by anterior transverse scanning in healthy subjects. Ultrasound Med Biol. 2011 Jan;37(1):44-52. doi: 10.1016/j.ultrasmedbio.2010.10.004. — View Citation

Ueki J, De Bruin PF, Pride NB. In vivo assessment of diaphragm contraction by ultrasound in normal subjects. Thorax. 1995 Nov;50(11):1157-61. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	respiratory muscle strength		Change from Baseline Respiratory Muscle Strength at 2 months	No
Secondary	Diafragmatic excursion and thickness of the diaphragm in the zone of apposition by ultrasonography	Ultrasound was used to evaluate diaphragm thickness non-invasively in the zone of apposition during tidal breathing and with changes in lung volume.; During respiration to total lung capacity, measurement of the diafragmatic excursion was made by ultrasonography.	Change from Baseline Diafragmatic Excursion and Thickness of the Diaphragm at 2 months	No