Creatine Supplementation and Cognition

Aging Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01164020
• Other study ID #: Creatine and Cognition
• Status: Completed
• Phase: N/A
• First received: July 15, 2010
• Last updated: January 17, 2013
• Start date: August 2010
• Est. completion date: December 2012

Study information

• Verified date: January 2013
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Resistance training as well as creatine supplementation may be beneficial for cognitive function, such as memory and attention. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on cognitive function in elderly women.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 56
• Est. completion date: December 2012
• Est. primary completion date: December 2012
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• women older than 60 years old

Exclusion Criteria:

• cardiovascular diseases or muscular disturbances precluding exercise training

• drugs affecting the cognition

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Aging
• Cognition

Intervention

Dietary Supplement:
• creatine supplementation
20g/d for 7 days followed by 5g/d for 23 weeks

Other:
• Placebo (Dextrose)
20g/d for 7 days followed by 5g/d for 23 weeks
• Resistance training
resistance training twice a week for 24 weeks

Locations

Country	Name	City	State
Brazil	School of Medicine - Division of Rheumatology	São Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cognitive function		six months	No
Secondary	physical capacity	muscle strength and function	six months	No