Aging Clinical Trial
Official title:
Frequency of Aerobic/Resistance Training in Older Women
The objective of this study is to provide insight into the effects combined training frequency has on improving fitness, ease of physical activity, and maintenance of a high total energy expenditure. Such information is critical to our understanding of ways to improve well-being, quality of life, and independence of an aging population. 105 participants will be enrolled in this study. The length of time for your involvement in the study will be 32 weeks. You will undergo the procedures listed in this consent form on 3 separate occasions-initially at your entry, at 16 weeks and again at 32 weeks.
Frequency of aerobic/resistance training in older women
Abstract Combined aerobic and resistance training have unique benefits for maintaining a
physical activity (PA). However, the optimal training program for combining these two modes
of training in older adults is unknown. This study builds on current and past studies
showing that training induced gains in aerobic fitness, muscle strength, and ease of PA are
important for maintaining an active lifestyle, a favorable body composition, and high bone
density. Traditionally 3 d/wk combined training has been felt to be optimal while recent
studies suggest 1 d/wk combined training may create similar adaptations as more frequent
training. However, our previous and ongoing studies suggest that 1 d/wk combined aerobic and
resistance training (C1) may be insufficient stimulus to induce optimal adaptations and that
3 d/wk combined training (C3) may be too frequent a stimulus for older adults. This study
will enable us to compare the effects of C1, 2 d/wk combined training (C2), and C3 on
fitness, body composition, ease of PA, PA, and total free-living energy expenditure (TEE).
We hypothesize that C2 will result in a larger increase in muscle size, bone density,
strength, aerobic capacity, power, ease of PA, PA, and TEE than either C1 or C3. Circulating
cytokines and psychological mood states linked to chronic overstress will also be examined.
Objectives: We will examine changes in circulating cytokines, mood states, muscle size, bone
density, aerobic capacity, strength, power, ease of PA, PA, and TEE following 16 and 32 wks
training. Design: We will to evaluate 78 (>60 yrs) Black and White women matched for age,
race, and BMI into C1, C2, or C3 groups prior to, after 16, and after 32 wks training. Women
will undergo evaluation of metabolic parameters in a General Clinical Research Center.
Significance: This study should provide insight into the effects combined training frequency
has on improving fitness, ease of PA, and maintenance of a high TEE. Such information is
critical to our understanding of ways to improve well being, quality of life, and
independence of an aging population.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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