Aging Clinical Trial
Official title:
A Trial to Reduce Delirium in Aged Post Acute Patients
Verified date | November 2006 |
Source | National Institute on Aging (NIA) |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
The purpose of this study is to develop a comprehensive Delirium Abatement Program of care of delirious patients in the post acute care setting and to evaluate its impact on persistence and severity of delirium and on functional recovery.
Status | Completed |
Enrollment | 500 |
Est. completion date | June 2004 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 65 Years and older |
Eligibility |
Inclusion Criteria: - Admission to study site following acute care medical/surgical hospitalization - Aged 65 or older - English-speaking - Communicative prior to acute illness - Not admitted for terminal care (life expectancy greater than 6 months) - Residence within 25 miles of research site Exclusion Criteria: - Significant hearing impairment which precludes interviews - End stage dementia (complete ADL dependence) - Previous study enrollment |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Hebrew Rehabilitation Center for Aged | Boston | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
National Institute on Aging (NIA) | Paul B. Beeson Career Development Awards in Aging Research Program |
United States,
Bergmann MA, Murphy KM, Kiely DK, Jones RN, Marcantonio ER. A model for management of delirious postacute care patients. J Am Geriatr Soc. 2005 Oct;53(10):1817-25. — View Citation
Levkoff SE, Evans DA, Liptzin B, Cleary PD, Lipsitz LA, Wetle TT, Reilly CH, Pilgrim DM, Schor J, Rowe J. Delirium. The occurrence and persistence of symptoms among elderly hospitalized patients. Arch Intern Med. 1992 Feb;152(2):334-40. — View Citation
Lipowski ZJ. Delirium in the elderly patient. N Engl J Med. 1989 Mar 2;320(9):578-82. Review. — View Citation
Marcantonio ER, Flacker JM, Michaels M, Resnick NM. Delirium is independently associated with poor functional recovery after hip fracture. J Am Geriatr Soc. 2000 Jun;48(6):618-24. — View Citation
Marcantonio ER, Kiely DK, Simon SE, John Orav E, Jones RN, Murphy KM, Bergmann MA. Outcomes of older people admitted to postacute facilities with delirium. J Am Geriatr Soc. 2005 Jun;53(6):963-9. — View Citation
Marcantonio ER, Simon SE, Bergmann MA, Jones RN, Murphy KM, Morris JN. Delirium symptoms in post-acute care: prevalent, persistent, and associated with poor functional recovery. J Am Geriatr Soc. 2003 Jan;51(1):4-9. — View Citation
Simon SE, Bergmann MA, Jones RN, Murphy KM, Orav EJ, Marcantonio ER. Reliability of a structured assessment for nonclinicians to detect delirium among new admissions to postacute care. J Am Med Dir Assoc. 2006 Sep;7(7):412-5. Epub 2006 May 30. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Prevalence of delirium at two weeks after admission | |||
Primary | Activities of Daily Living (ADL) functional improvement two weeks after admission | |||
Primary | Full ADL functional recovery to pre-illness status three months after post-acute admission | |||
Secondary | Examination of differences between patients in facilities receiving the Delirium Abatement Program and those not on additional outcomes of delirium persistence and ADL improvement one month following admission | |||
Secondary | Differences in delirium severity, length of post acute stay, and health care resource utilization |
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