Aging Clinical Trial
There are more and more macromastic women in Taiwan, which may due to the high cholesterol foods. Patients with macromastia not only suffered from physical problems but also psychological discomforts.
Large breasts cause neck and back pain, irritating grooves, cut in the skin of the shoulders
by the pressure of brassiere straps, breast pain, and maceration and dermatoses in the
inframammary region. From a psychological point of view, excessively large breasts can be
troublesome focus of embarrassment for the teenager as well as the woman in her senior
years. Unilateral hypertrophy with asymmetry heightens embarrassment. Thus, patients seek to
reduce the size of their breasts.
In the human female, variant receptors were detected in epithelial cells in normal breast
tissue, benign breast lesions, breast carcinoma tissue, and breast cancer cell lines2-11.
The cause of the difference in breast development status is still unclear. Abnormalities at
the tissue receptor level may be important in the pathophysiology of macromastia. This study
aimed to make clear the difference in variant receptor levels between breast hypertrophy
patients and macromastia ones by examining the receptor levels in breast tissue. Then, we
could explore the possible etiology of mammary hypertrophy and macromastia.
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Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Educational/Counseling/Training
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